Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6H76_RS03470 Genome accession   NZ_CP065994
Coordinates   689805..691103 (-) Length   432 a.a.
NCBI ID   WP_006531182.1    Uniprot ID   A0A380KKP6
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 684805..696103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS03460 (I6H76_03460) hpf 688518..689066 (-) 549 WP_006531184.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6H76_RS03465 (I6H76_03465) - 689143..689805 (-) 663 WP_006531183.1 ComF family protein -
  I6H76_RS03470 (I6H76_03470) comFA/cflA 689805..691103 (-) 1299 WP_006531182.1 DEAD/DEAH box helicase Machinery gene
  I6H76_RS03475 (I6H76_03475) - 691158..691784 (+) 627 WP_006531181.1 YigZ family protein -
  I6H76_RS03480 (I6H76_03480) cysK 691884..692813 (+) 930 WP_006531180.1 cysteine synthase A -
  I6H76_RS03485 (I6H76_03485) - 692914..693270 (-) 357 WP_006531179.1 S1 RNA-binding domain-containing protein -
  I6H76_RS03490 (I6H76_03490) - 693270..694670 (-) 1401 WP_081442254.1 Cof-type HAD-IIB family hydrolase -
  I6H76_RS03495 (I6H76_03495) - 694794..695438 (-) 645 WP_006531177.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49196.44 Da        Isoelectric Point: 9.9299

>NTDB_id=516116 I6H76_RS03470 WP_006531182.1 689805..691103(-) (comFA/cflA) [Streptococcus infantarius strain FDAARGOS_1019]
MTELNDYYGRIFTESQLTDDLKKEAKVLPSVKKEKGQMICNRCGSVMAANQMLQTGRIYCRECLVFRRNTSDSNLYYFPQ
KPFTKTQSLNWQGKLTSYQDEVSKGMLAGITEKQDLLIHAVTGAGKTEMIYQSLAKVIDNGGSVCLASPRIDVCLELYKR
LSRDFSCPITLLHGNSELYKRSQLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVNQSLKDDGVKLFLTATST
DELDKKVKKGELTKLHLARRFHANPLVVPKMVWLSKVLISMKKKKFPPKLISLLKKQRQSQFPLLIFFPNIEQGREFTSI
FQTTFPDERIGFVSSKTENRLELVEEFRQGKLTILVTTTILERGVTFPCVDVFVLLANHKLYSKSALVQISGRVGRAAER
PTGELLFLHDGVTKAMKKAISEIKEMNHKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=516116 I6H76_RS03470 WP_006531182.1 689805..691103(-) (comFA/cflA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGACAGAGTTGAATGATTACTATGGAAGAATTTTTACAGAAAGTCAATTAACAGATGACTTGAAAAAGGAAGCAAAAGT
CCTTCCTTCGGTTAAAAAGGAAAAAGGTCAAATGATTTGTAATCGCTGTGGAAGTGTAATGGCAGCAAATCAAATGTTGC
AAACTGGTCGCATTTATTGTAGAGAGTGTTTAGTTTTTAGGCGAAATACTAGTGATTCTAATCTTTATTATTTCCCTCAG
AAGCCTTTTACAAAGACTCAGTCGTTAAATTGGCAAGGAAAACTAACTTCTTATCAAGATGAAGTTTCTAAAGGCATGCT
TGCAGGTATTACAGAAAAACAAGATTTATTGATTCACGCTGTGACTGGTGCTGGTAAAACTGAAATGATTTATCAATCTC
TAGCTAAAGTTATTGATAATGGTGGAAGTGTCTGCTTAGCGAGTCCACGGATTGATGTTTGTTTAGAACTTTATAAACGA
TTATCAAGAGATTTTTCTTGTCCAATTACACTTTTACATGGTAATTCTGAGCTGTATAAACGCTCTCAGTTGGTAATTGC
AACGACCCATCAGCTTTTAAAATTTTACCGAGCTTTTGATTTATTAATCATCGACGAAGTTGATGCCTTTCCCTTTGTTG
ATAATAAAATGCTTTATTACGCTGTCAATCAATCGCTAAAAGATGATGGCGTTAAACTCTTTTTAACAGCGACTTCGACT
GATGAACTTGATAAAAAGGTGAAAAAAGGAGAGTTGACAAAGCTGCATTTGGCAAGACGTTTTCATGCCAATCCTTTGGT
AGTCCCCAAAATGGTTTGGTTAAGCAAAGTGCTAATTTCAATGAAAAAGAAAAAATTTCCTCCTAAACTAATCTCTCTTT
TAAAAAAACAAAGGCAAAGCCAGTTTCCACTTCTCATATTTTTCCCAAATATTGAACAAGGTAGAGAATTTACAAGTATC
TTTCAAACCACTTTTCCAGATGAAAGGATAGGATTTGTATCAAGTAAAACTGAAAATCGTTTGGAATTGGTAGAAGAATT
TAGACAAGGAAAATTAACCATACTAGTGACGACAACCATTCTAGAACGTGGGGTAACCTTTCCTTGTGTCGATGTTTTTG
TTCTACTTGCAAATCATAAATTGTACAGCAAAAGTGCACTTGTTCAGATTTCTGGTCGAGTTGGACGAGCAGCCGAGAGA
CCGACAGGAGAGCTATTGTTCTTGCATGATGGCGTAACAAAAGCTATGAAAAAAGCTATTTCTGAAATAAAAGAAATGAA
TCATAAAGGAGGTTTTTAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KKP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.953

98.843

0.593
  comFA/cflA Streptococcus pneumoniae D39

59.953

98.843

0.593
  comFA/cflA Streptococcus pneumoniae R6

59.953

98.843

0.593
  comFA/cflA Streptococcus mitis NCTC 12261

59.953

98.843

0.593
  comFA/cflA Streptococcus pneumoniae TIGR4

59.953

98.843

0.593
  comFA/cflA Streptococcus mitis SK321

59.251

98.843

0.586
  comFA Lactococcus lactis subsp. cremoris KW2

49.292

98.148

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

37.385

100

0.377