Detailed information NTG0515966

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I6I21_RS06805
• Genome accession: NZ_CP065984
• Coordinates: 1356783..1357811 (+)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis strain FDAARGOS_1064
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1351783..1362811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I21_RS06780 (I6I21_06780)	-	1352331..1352825 (-)	495	WP_012898649.1	RNA polymerase sigma factor	-
I6I21_RS06785 (I6I21_06785)	lmrP	1353013..1354237 (+)	1225	Protein_1301	multidrug efflux MFS transporter LmrP	-
I6I21_RS06790 (I6I21_06790)	-	1354321..1355541 (+)	1221	WP_003132654.1	MDR family MFS transporter	-
I6I21_RS06795 (I6I21_06795)	rsmD	1355712..1356251 (+)	540	WP_003132655.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I6I21_RS06800 (I6I21_06800)	coaD	1356299..1356796 (+)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
I6I21_RS06805 (I6I21_06805)	sepM	1356783..1357811 (+)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
I6I21_RS06810 (I6I21_06810)	-	1357932..1358789 (+)	858	WP_003132658.1	Rgg/GadR/MutR family transcriptional regulator	-
I6I21_RS06815 (I6I21_06815)	-	1358973..1361015 (+)	2043	WP_228763148.1	radical SAM protein	-
I6I21_RS06820 (I6I21_06820)	-	1361008..1361835 (+)	828	WP_014570829.1	radical SAM protein	-
I6I21_RS06825 (I6I21_06825)	-	1361832..1362041 (+)	210	WP_003132661.1	hypothetical protein	-
I6I21_RS06830 (I6I21_06830)	-	1362028..1362525 (+)	498	WP_003132662.1	nitroreductase family protein	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=515966 I6I21_RS06805 WP_003132657.1 1356783..1357811(+) (sepM) [Lactococcus lactis strain FDAARGOS_1064]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=515966 I6I21_RS06805 WP_003132657.1 1356783..1357811(+) (sepM) [Lactococcus lactis strain FDAARGOS_1064]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACAAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGAAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
GACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTGGTGCCTGACTCAGGCACCAAAAAAGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491