Detailed information NTG0515364

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: JAN99_RS03055
• Genome accession: NZ_CP065927
• Coordinates: 606086..607123 (+)
• Length: 345 a.a.
• NCBI ID: WP_111693301.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm9ST603
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 601086..612123

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JAN99_RS03030 (JAN99_03025)	-	601349..602680 (+)	1332	WP_032460502.1	dipeptidase	-
JAN99_RS03035 (JAN99_03030)	arcC	602700..603650 (+)	951	WP_009880962.1	carbamate kinase	-
JAN99_RS03040 (JAN99_03035)	asnA	603964..604956 (+)	993	WP_136116273.1	aspartate--ammonia ligase	-
JAN99_RS03045 (JAN99_03040)	rsmD	605079..605618 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
JAN99_RS03050 (JAN99_03045)	coaD	605608..606099 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
JAN99_RS03055 (JAN99_03050)	sepM	606086..607123 (+)	1038	WP_111693301.1	SepM family pheromone-processing serine protease	Regulator
JAN99_RS03060 (JAN99_03055)	-	607528..608505 (+)	978	WP_109991723.1	LacI family DNA-binding transcriptional regulator	-
JAN99_RS03065 (JAN99_03060)	-	608953..609573 (+)	621	WP_002992791.1	YutD family protein	-
JAN99_RS03070 (JAN99_03065)	rlmN	609577..610656 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
JAN99_RS03075 (JAN99_03070)	-	610738..611364 (-)	627	WP_136116275.1	A24 family peptidase	-
JAN99_RS03080 (JAN99_03075)	-	611592..612119 (+)	528	WP_002983837.1	Dps family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37527.22 Da
• Isoelectric Point: 9.6692

>NTDB_id=515364 JAN99_RS03055 WP_111693301.1 606086..607123(+) (sepM) [Streptococcus pyogenes strain emm9ST603]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRSVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=515364 JAN99_RS03055 WP_111693301.1 606086..607123(+) (sepM) [Streptococcus pyogenes strain emm9ST603]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGTCTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696