Detailed information NTG0515247

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JC285_RS04375
• Genome accession: NZ_CP065924
• Coordinates: 972728..973771 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain SP_11304-2A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 967728..978771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC285_RS04350 (JC285_04350)	-	967984..968706 (+)	723	WP_014613476.1	glutamine amidotransferase	-
JC285_RS04355 (JC285_04355)	-	969674..970672 (-)	999	WP_037542644.1	aromatic acid exporter family protein	-
JC285_RS04360 (JC285_04360)	map	970769..971530 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
JC285_RS04365 (JC285_04365)	-	971628..972017 (+)	390	WP_014613479.1	hypothetical protein	-
JC285_RS04370 (JC285_04370)	liaF	972030..972731 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
JC285_RS04375 (JC285_04375)	vraS	972728..973771 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
JC285_RS04380 (JC285_04380)	vraR	973761..974390 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
JC285_RS04385 (JC285_04385)	-	975003..976322 (-)	1320	WP_198461321.1	ISL3 family transposase	-
JC285_RS04390 (JC285_04390)	-	976449..977030 (-)	582	WP_070407816.1	carbonic anhydrase	-
JC285_RS04395 (JC285_04395)	-	977063..978400 (-)	1338	WP_198462671.1	YihY/virulence factor BrkB family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=515247 JC285_RS04375 WP_014613481.1 972728..973771(+) (vraS) [Staphylococcus pseudintermedius strain SP_11304-2A]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=515247 JC285_RS04375 WP_014613481.1 972728..973771(+) (vraS) [Staphylococcus pseudintermedius strain SP_11304-2A]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839