Detailed information NTG0515183

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JC281_RS04125
• Genome accession: NZ_CP065920
• Coordinates: 927709..928752 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain SP_11306-1A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 922709..933752

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC281_RS04100 (JC281_04100)	-	922965..923687 (+)	723	WP_014613476.1	type 1 glutamine amidotransferase	-
JC281_RS04105 (JC281_04105)	-	924655..925653 (-)	999	WP_014613477.1	FUSC family protein	-
JC281_RS04110 (JC281_04110)	map	925750..926511 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
JC281_RS04115 (JC281_04115)	-	926609..926998 (+)	390	WP_014613479.1	hypothetical protein	-
JC281_RS04120 (JC281_04120)	liaF	927011..927712 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
JC281_RS04125 (JC281_04125)	vraS	927709..928752 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
JC281_RS04130 (JC281_04130)	vraR	928742..929371 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
JC281_RS04135 (JC281_04135)	-	929938..930519 (-)	582	WP_063278570.1	beta-class carbonic anhydrase	-
JC281_RS04140 (JC281_04140)	-	930552..931889 (-)	1338	WP_037542645.1	YihY/virulence factor BrkB family protein	-
JC281_RS04145 (JC281_04145)	-	932105..932392 (-)	288	WP_014613485.1	YtxH domain-containing protein	-
JC281_RS04150 (JC281_04150)	-	932400..932858 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
JC281_RS04155 (JC281_04155)	-	932992..933195 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=515183 JC281_RS04125 WP_014613481.1 927709..928752(+) (vraS) [Staphylococcus pseudintermedius strain SP_11306-1A]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=515183 JC281_RS04125 WP_014613481.1 927709..928752(+) (vraS) [Staphylococcus pseudintermedius strain SP_11306-1A]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTTTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTCGAGCTGTATAATGAAACGATTGAATT
ATATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGAATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839