Detailed information NTG0515152

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JC284_RS04105
• Genome accession: NZ_CP065919
• Coordinates: 922769..923812 (+)
• Length: 347 a.a.
• NCBI ID: WP_014613481.1
• Uniprot ID: -
• Organism: Staphylococcus pseudintermedius strain SP_11306-4A
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 917769..928812

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC284_RS04080 (JC284_04080)	-	918024..918746 (+)	723	WP_014613476.1	glutamine amidotransferase	-
JC284_RS04085 (JC284_04085)	-	919715..920713 (-)	999	WP_014613477.1	aromatic acid exporter family protein	-
JC284_RS04090 (JC284_04090)	map	920810..921571 (+)	762	WP_014613478.1	type I methionyl aminopeptidase	-
JC284_RS04095 (JC284_04095)	-	921669..922058 (+)	390	WP_014613479.1	hypothetical protein	-
JC284_RS04100 (JC284_04100)	liaF	922071..922772 (+)	702	WP_014613480.1	cell wall-active antibiotics response protein LiaF	-
JC284_RS04105 (JC284_04105)	vraS	922769..923812 (+)	1044	WP_014613481.1	sensor histidine kinase	Regulator
JC284_RS04110 (JC284_04110)	vraR	923802..924431 (+)	630	WP_014613482.1	response regulator transcription factor	Regulator
JC284_RS04115 (JC284_04115)	-	925006..925587 (-)	582	WP_115895379.1	carbonic anhydrase	-
JC284_RS04120 (JC284_04120)	-	925620..926957 (-)	1338	WP_115895380.1	YihY/virulence factor BrkB family protein	-
JC284_RS04125 (JC284_04125)	-	927173..927460 (-)	288	WP_101431679.1	YtxH domain-containing protein	-
JC284_RS04130 (JC284_04130)	-	927468..927926 (-)	459	WP_014613486.1	low molecular weight protein-tyrosine-phosphatase	-
JC284_RS04135 (JC284_04135)	-	928060..928263 (+)	204	WP_014613487.1	DUF1128 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39939.24 Da
• Isoelectric Point: 5.0435

>NTDB_id=515152 JC284_RS04105 WP_014613481.1 922769..923812(+) (vraS) [Staphylococcus pseudintermedius strain SP_11306-4A]
MNHYVRAIGSMLILVYSMLTAFFFIDKVFTNIIFFQGMFYTQILGIPVFIFLNLVVIFLCIIVGSVLAYKINQQNDWLKQ
QIVRAFEGETVGINDQQLELYNETIELYQALVPLNQELHKMRIKTQNLTNETYNLNDLKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETDLAPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKSLVTDLQRKVPIKVVQEI
DEFEVPKGIEDHLFRITQEAISNTLRHAEGTQVTVELLNRNDYLLLRIQDDGIGFNVDEKLEQSYGLKNMRERAIEIGAT
FHIVSLPDAGTRIEVKAPLEKEEQHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=515152 JC284_RS04105 WP_014613481.1 922769..923812(+) (vraS) [Staphylococcus pseudintermedius strain SP_11306-4A]
ATGAATCACTACGTCCGAGCGATAGGTTCGATGCTCATTCTCGTATATAGTATGCTCACCGCGTTTTTCTTTATTGACAA
AGTGTTCACCAATATTATTTTCTTTCAAGGCATGTTTTATACACAAATTTTAGGTATTCCTGTTTTTATCTTTTTAAATT
TAGTCGTCATTTTTTTATGTATTATTGTGGGCAGTGTGTTAGCTTATAAAATCAATCAACAAAATGATTGGCTCAAGCAA
CAAATCGTTCGTGCCTTTGAAGGTGAAACAGTGGGCATCAATGATCAACAACTTGAGCTGTATAATGAAACGATTGAATT
GTATCAAGCACTCGTCCCATTAAATCAAGAATTGCATAAAATGCGGATTAAAACACAAAATTTAACGAATGAAACGTATA
ATTTAAATGATTTGAAGGTGAAAAAGATTATAGAAGATGAACGACAGCGTTTAGCACGAGAATTGCATGATAGTGTGTCG
CAACAACTTTTCGCGGCAAGTATGATGTTGTCTGCAATCAAAGAAACAGATTTAGCACCACCGTTAGACCAACAAATTCC
AACGTTAGAAAAAATGGTGCAAGACTCACAACTTGAAATGCGCGCTCTGTTACTTCACTTGAGACCTATAGGATTGAAGG
ACAAATCGTTAGGTGAGGGAATTAAATCGCTTGTGACGGATCTACAACGTAAAGTACCCATTAAAGTCGTGCAAGAAATT
GATGAGTTTGAAGTACCTAAAGGCATTGAGGATCACCTTTTTAGAATTACCCAAGAAGCGATTTCCAATACGTTACGACA
TGCTGAGGGGACGCAAGTAACGGTAGAATTACTTAACCGCAATGATTATTTATTGTTGCGTATACAAGATGACGGCATTG
GATTTAATGTCGATGAAAAGTTAGAACAAAGTTATGGATTAAAAAATATGCGTGAACGTGCAATAGAGATTGGTGCCACA
TTTCATATCGTCTCATTACCTGATGCGGGGACGAGAATAGAAGTGAAAGCACCACTTGAAAAGGAGGAACAGCATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-341)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	83.862	100	0.839