Detailed information NTG0515012

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: I1A60_RS13490
• Genome accession: NZ_CP065857
• Coordinates: 2725183..2726070 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CC1153-MRSA
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2720183..2731070

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I1A60_RS13460 (I1A60_13460)	-	2720202..2720294 (+)	93	WP_010956583.1	hypothetical protein	-
I1A60_RS13465 (I1A60_13465)	-	2720402..2720899 (-)	498	WP_001065268.1	glutathione peroxidase	-
I1A60_RS13470 (I1A60_13470)	-	2720909..2721169 (-)	261	WP_001791974.1	hypothetical protein	-
I1A60_RS13475 (I1A60_13475)	-	2721551..2721664 (-)	114	WP_011447078.1	hypothetical protein	-
I1A60_RS13480 (I1A60_13480)	-	2722323..2724323 (-)	2001	WP_000776751.1	ABC transporter permease	-
I1A60_RS13485 (I1A60_13485)	-	2724320..2725075 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
I1A60_RS13490 (I1A60_13490)	braS	2725183..2726070 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
I1A60_RS13495 (I1A60_13495)	braR	2726081..2726746 (-)	666	WP_151359682.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
I1A60_RS13500 (I1A60_13500)	-	2726772..2726972 (-)	201	WP_000604727.1	hypothetical protein	-
I1A60_RS13505 (I1A60_13505)	-	2727170..2728595 (+)	1426	Protein_2630	alkaline phosphatase	-
I1A60_RS14100	-	2728655..2728756 (-)	102	WP_000731972.1	SE2200 family small protein	-
I1A60_RS13515 (I1A60_13515)	-	2728878..2729333 (-)	456	WP_072468518.1	MarR family winged helix-turn-helix transcriptional regulator	-
I1A60_RS13520 (I1A60_13520)	-	2729578..2730339 (-)	762	WP_023914305.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=515012 I1A60_RS13490 WP_000143419.1 2725183..2726070(-) (braS) [Staphylococcus aureus strain CC1153-MRSA]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=515012 I1A60_RS13490 WP_000143419.1 2725183..2726070(-) (braS) [Staphylococcus aureus strain CC1153-MRSA]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997