Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I1A60_RS10425 Genome accession   NZ_CP065857
Coordinates   2116913..2117629 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain CC1153-MRSA     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2111913..2122629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I1A60_RS10395 (I1A60_10395) - 2112130..2112756 (+) 627 WP_072468680.1 nitroreductase family protein -
  I1A60_RS10400 (I1A60_10400) - 2113117..2113902 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  I1A60_RS14090 hld 2114502..2114582 (-) 81 WP_000046022.1 delta-hemolysin -
  I1A60_RS10410 (I1A60_10410) - 2114872..2115435 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  I1A60_RS10415 (I1A60_10415) agrD 2115438..2115581 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  I1A60_RS10420 (I1A60_10420) agrC 2115611..2116894 (+) 1284 WP_151359710.1 quorum-sensing sensor histidine kinase AgrC -
  I1A60_RS10425 (I1A60_10425) agrA 2116913..2117629 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  I1A60_RS10430 (I1A60_10430) - 2117701..2117810 (+) 110 Protein_2028 hypothetical protein -
  I1A60_RS10435 (I1A60_10435) - 2117998..2118957 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  I1A60_RS10440 (I1A60_10440) - 2118954..2120438 (-) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  I1A60_RS10445 (I1A60_10445) - 2120587..2121537 (-) 951 WP_072468682.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=515008 I1A60_RS10425 WP_000688492.1 2116913..2117629(+) (agrA) [Staphylococcus aureus strain CC1153-MRSA]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=515008 I1A60_RS10425 WP_000688492.1 2116913..2117629(+) (agrA) [Staphylococcus aureus strain CC1153-MRSA]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1