Detailed information NTG0051466

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SSUST1_RS02530
• Genome accession: NC_017950
• Coordinates: 495508..497736 (-)
• Length: 742 a.a.
• NCBI ID: WP_014735553.1
• Uniprot ID: -
• Organism: Streptococcus suis ST1
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 490508..502736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUST1_RS02515 (SSUST1_0490)	-	492716..493918 (-)	1203	WP_079759536.1	IS110 family transposase	-
SSUST1_RS02520 (SSUST1_0491)	-	494471..494806 (-)	336	WP_013730208.1	DUF1827 family protein	-
SSUST1_RS02525 (SSUST1_0492)	-	494861..495322 (-)	462	WP_014735552.1	NUDIX hydrolase	-
SSUST1_RS02530 (SSUST1_0493)	clpE	495508..497736 (-)	2229	WP_014735553.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSUST1_RS02535 (SSUST1_0494)	-	497960..498190 (+)	231	WP_014735554.1	DUF1797 family protein	-
SSUST1_RS02540 (SSUST1_0495)	-	498316..499005 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
SSUST1_RS02545 (SSUST1_0496)	-	498998..499735 (+)	738	WP_014735555.1	amino acid ABC transporter ATP-binding protein	-
SSUST1_RS02550 (SSUST1_0497)	-	499865..500713 (+)	849	WP_014735556.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SSUST1_RS02555 (SSUST1_0499)	-	502143..502442 (+)	300	WP_014735557.1	hypothetical protein	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82628.06 Da
• Isoelectric Point: 5.4291

>NTDB_id=51466 SSUST1_RS02530 WP_014735553.1 495508..497736(-) (clpE) [Streptococcus suis ST1]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASNLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHLTDKVKEKLVDLGYDPKMGARPLRRTIQYQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=51466 SSUST1_RS02530 WP_014735553.1 495508..497736(-) (clpE) [Streptococcus suis ST1]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACCCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGAGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTGGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCTGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTAACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATGCCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGC
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGTATCAGCCTCCATTTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAATATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• AAA lid domain (AAA_lid_9) (291-389)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.095	100	0.834
clpE	Streptococcus pneumoniae D39	82.095	100	0.834
clpE	Streptococcus pneumoniae R6	82.095	100	0.834
clpE	Streptococcus pneumoniae TIGR4	82.095	100	0.834
clpE	Streptococcus mutans UA159	81.976	100	0.827
clpC	Lactococcus lactis subsp. cremoris KW2	77.379	97.709	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	52.462	87.601	0.46
clpC	Streptococcus thermophilus LMD-9	48.089	84.636	0.407
clpC	Streptococcus mutans UA159	48.397	84.097	0.407
clpC	Streptococcus thermophilus LMG 18311	47.771	84.636	0.404
clpC	Streptococcus pneumoniae Rx1	47.84	84.232	0.403
clpC	Streptococcus pneumoniae D39	47.84	84.232	0.403
clpC	Streptococcus pneumoniae TIGR4	47.84	84.232	0.403
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.815	84.636	0.396