Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | I7831_RS02495 | Genome accession | NZ_CP065797 |
| Coordinates | 497075..498700 (-) | Length | 541 a.a. |
| NCBI ID | WP_194376034.1 | Uniprot ID | - |
| Organism | Staphylococcus saprophyticus strain GDY8P168P | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 491808..556930 | 497075..498700 | within | 0 |
Gene organization within MGE regions
Location: 491808..556930
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I7831_RS02455 (I7831_02455) | mecA | 491808..493817 (+) | 2010 | WP_194376038.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| I7831_RS02460 (I7831_02460) | - | 493863..494246 (-) | 384 | WP_194376062.1 | MaoC family dehydratase | - |
| I7831_RS02465 (I7831_02465) | - | 494237..494602 (+) | 366 | Protein_473 | CDP-glycerol glycerophosphotransferase family protein | - |
| I7831_RS02470 (I7831_02470) | - | 494679..494900 (-) | 222 | WP_023604758.1 | hypothetical protein | - |
| I7831_RS02475 (I7831_02475) | - | 494915..495424 (-) | 510 | WP_194376037.1 | DUF1643 domain-containing protein | - |
| I7831_RS02480 (I7831_02480) | - | 495442..495753 (-) | 312 | WP_194376036.1 | DUF960 family protein | - |
| I7831_RS02485 (I7831_02485) | - | 495840..496190 (-) | 351 | WP_194376035.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I7831_RS02490 (I7831_02490) | - | 496765..497040 (+) | 276 | WP_052734120.1 | hypothetical protein | - |
| I7831_RS02495 (I7831_02495) | ccrB | 497075..498700 (-) | 1626 | WP_194376034.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I7831_RS02500 (I7831_02500) | ccrA | 498697..500064 (-) | 1368 | WP_194376033.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I7831_RS02505 (I7831_02505) | - | 500291..502450 (+) | 2160 | WP_194376032.1 | AAA family ATPase | - |
| I7831_RS02510 (I7831_02510) | - | 502755..503189 (+) | 435 | WP_103388680.1 | hypothetical protein | - |
| I7831_RS02515 (I7831_02515) | - | 503219..503956 (+) | 738 | WP_107391432.1 | Cthe_2314 family HEPN domain-containing protein | - |
| I7831_RS02520 (I7831_02520) | - | 504143..505468 (+) | 1326 | WP_119609958.1 | DUF6038 family protein | - |
| I7831_RS02525 (I7831_02525) | - | 505679..506779 (+) | 1101 | WP_198065279.1 | DNA polymerase | - |
| I7831_RS02530 (I7831_02530) | - | 506772..507140 (+) | 369 | WP_031864395.1 | hypothetical protein | - |
| I7831_RS02535 (I7831_02535) | - | 507140..508780 (+) | 1641 | WP_198065280.1 | DUF5906 domain-containing protein | - |
| I7831_RS02540 (I7831_02540) | ccrC | 509005..510687 (+) | 1683 | WP_011302048.1 | cassette chromosome recombinase CcrC | - |
| I7831_RS02545 (I7831_02545) | - | 510786..511124 (+) | 339 | WP_053041968.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I7831_RS02550 (I7831_02550) | - | 511220..511531 (+) | 312 | WP_198065281.1 | DUF960 family protein | - |
| I7831_RS02555 (I7831_02555) | - | 511553..512056 (+) | 504 | WP_198065282.1 | DUF1643 domain-containing protein | - |
| I7831_RS02560 (I7831_02560) | - | 512197..512367 (+) | 171 | WP_198065283.1 | hypothetical protein | - |
| I7831_RS02565 (I7831_02565) | - | 512530..512748 (+) | 219 | WP_198065284.1 | hypothetical protein | - |
| I7831_RS13435 | - | 512773..513240 (+) | 468 | WP_232334972.1 | hypothetical protein | - |
| I7831_RS02575 (I7831_02575) | - | 513293..513646 (-) | 354 | Protein_495 | type I restriction enzyme endonuclease domain-containing protein | - |
| I7831_RS02580 (I7831_02580) | - | 513721..514389 (+) | 669 | WP_198065285.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| I7831_RS02585 (I7831_02585) | - | 514403..515089 (+) | 687 | WP_198065286.1 | polysaccharide biosynthesis tyrosine autokinase | - |
| I7831_RS02590 (I7831_02590) | - | 515089..515853 (+) | 765 | WP_198065287.1 | tyrosine-protein phosphatase | - |
| I7831_RS02595 (I7831_02595) | - | 515877..517712 (+) | 1836 | WP_198065288.1 | polysaccharide biosynthesis protein | - |
| I7831_RS02600 (I7831_02600) | - | 517724..518752 (+) | 1029 | WP_198065289.1 | nucleoside-diphosphate sugar epimerase/dehydratase | - |
| I7831_RS02605 (I7831_02605) | - | 518762..519874 (+) | 1113 | WP_198065290.1 | NAD-dependent epimerase/dehydratase family protein | - |
| I7831_RS02610 (I7831_02610) | wecB | 519876..521000 (+) | 1125 | WP_198065291.1 | non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase | - |
| I7831_RS02615 (I7831_02615) | - | 521083..522330 (+) | 1248 | WP_198065292.1 | O-antigen ligase family protein | - |
| I7831_RS02620 (I7831_02620) | - | 522330..523439 (+) | 1110 | WP_198065293.1 | glycosyltransferase | - |
| I7831_RS02625 (I7831_02625) | - | 523436..524650 (+) | 1215 | WP_198065294.1 | oligosaccharide flippase family protein | - |
| I7831_RS02630 (I7831_02630) | - | 524654..525934 (+) | 1281 | WP_198065295.1 | UDP-glucose dehydrogenase family protein | - |
| I7831_RS02635 (I7831_02635) | - | 526110..527315 (+) | 1206 | WP_198065296.1 | glycosyltransferase family 4 protein | - |
| I7831_RS02640 (I7831_02640) | - | 527328..527885 (+) | 558 | WP_198065297.1 | sugar transferase | - |
| I7831_RS02645 (I7831_02645) | - | 527885..528769 (+) | 885 | WP_198065298.1 | NAD-dependent epimerase/dehydratase family protein | - |
| I7831_RS02650 (I7831_02650) | - | 529250..531103 (+) | 1854 | WP_228481683.1 | DNA adenine methylase | - |
| I7831_RS02655 (I7831_02655) | - | 531096..532232 (+) | 1137 | WP_194441015.1 | HNH endonuclease signature motif containing protein | - |
| I7831_RS13440 | - | 532513..532998 (-) | 486 | WP_228481682.1 | hypothetical protein | - |
| I7831_RS02665 (I7831_02665) | - | 533018..533671 (-) | 654 | WP_071331190.1 | hypothetical protein | - |
| I7831_RS02670 (I7831_02670) | - | 533776..534282 (-) | 507 | WP_198065299.1 | DUF1643 domain-containing protein | - |
| I7831_RS02675 (I7831_02675) | - | 534296..534607 (-) | 312 | WP_057510703.1 | DUF960 family protein | - |
| I7831_RS02680 (I7831_02680) | - | 534703..535041 (-) | 339 | WP_053464901.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I7831_RS02685 (I7831_02685) | - | 535596..535883 (+) | 288 | WP_103266532.1 | hypothetical protein | - |
| I7831_RS02690 (I7831_02690) | ccrB | 535919..537547 (-) | 1629 | WP_107519036.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I7831_RS02695 (I7831_02695) | ccrA | 537568..538917 (-) | 1350 | WP_198065300.1 | cassette chromosome recombinase CcrA | Machinery gene |
| I7831_RS02700 (I7831_02700) | - | 539117..539755 (-) | 639 | Protein_520 | hypothetical protein | - |
| I7831_RS02705 (I7831_02705) | - | 539755..540102 (+) | 348 | Protein_521 | recombinase family protein | - |
| I7831_RS02710 (I7831_02710) | - | 540214..540573 (-) | 360 | WP_046465687.1 | hypothetical protein | - |
| I7831_RS02715 (I7831_02715) | - | 540780..541106 (+) | 327 | WP_000391495.1 | ArsR/SmtB family transcription factor | - |
| I7831_RS02720 (I7831_02720) | - | 541409..543334 (+) | 1926 | WP_070657144.1 | heavy metal translocating P-type ATPase | - |
| I7831_RS02725 (I7831_02725) | - | 544430..545698 (+) | 1269 | WP_113342709.1 | adenylate/guanylate cyclase domain-containing protein | - |
| I7831_RS02730 (I7831_02730) | - | 545704..546180 (+) | 477 | WP_113342718.1 | Pycsar system effector family protein | - |
| I7831_RS02735 (I7831_02735) | - | 546220..547734 (+) | 1515 | WP_113342710.1 | type I restriction-modification system subunit M | - |
| I7831_RS02740 (I7831_02740) | - | 547724..548887 (+) | 1164 | WP_113342711.1 | restriction endonuclease subunit S | - |
| I7831_RS02745 (I7831_02745) | - | 548871..551993 (+) | 3123 | WP_165622421.1 | type I restriction endonuclease subunit R | - |
| I7831_RS02750 (I7831_02750) | - | 552189..552701 (-) | 513 | WP_107556504.1 | DUF1643 domain-containing protein | - |
| I7831_RS02755 (I7831_02755) | - | 552719..553030 (-) | 312 | WP_069855724.1 | DUF960 family protein | - |
| I7831_RS02760 (I7831_02760) | - | 553115..553465 (-) | 351 | WP_107556505.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| I7831_RS02765 (I7831_02765) | ccrB | 553934..555559 (-) | 1626 | WP_165622422.1 | cassette chromosome recombinase CcrB | Machinery gene |
| I7831_RS02770 (I7831_02770) | ccrA | 555581..556930 (-) | 1350 | WP_107601341.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 541 a.a. Molecular weight: 62424.00 Da Isoelectric Point: 9.9129
>NTDB_id=514656 I7831_RS02495 WP_194376034.1 497075..498700(-) (ccrB) [Staphylococcus saprophyticus strain GDY8P168P]
MKNVKKKRIGLYARVSTEMQTDGYSIQGQLNQLKDYCQFQGYEVVDEYTDRGISGKTTQRPELQRMLKDAKENKLDCIMV
YKTNRLARNTSDLLSIVEKLYKLNVEFFSLTEKIEIATSTGKLMLQILASFSEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKIPDSKKELMINQHEAHIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDKALWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKKLVEKINEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIHQLKQDKQAEALHYDADMIVNVLQAIFKDIDKLEKSQLKS
LYLTVIDRIDIRKHEHHKKQFYVTLKLNNEIIKQLFNNHPLDEVLLSTSSLFLPQTLYLTI
MKNVKKKRIGLYARVSTEMQTDGYSIQGQLNQLKDYCQFQGYEVVDEYTDRGISGKTTQRPELQRMLKDAKENKLDCIMV
YKTNRLARNTSDLLSIVEKLYKLNVEFFSLTEKIEIATSTGKLMLQILASFSEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKIPDSKKELMINQHEAHIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDKALWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKKLVEKINEKSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLDSVLKPTILSYQDELNQINNQIHQLKQDKQAEALHYDADMIVNVLQAIFKDIDKLEKSQLKS
LYLTVIDRIDIRKHEHHKKQFYVTLKLNNEIIKQLFNNHPLDEVLLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1626 bp
>NTDB_id=514656 I7831_RS02495 WP_194376034.1 497075..498700(-) (ccrB) [Staphylococcus saprophyticus strain GDY8P168P]
GTGAAAAATGTAAAGAAAAAACGTATTGGATTATACGCACGTGTATCGACTGAAATGCAAACGGATGGATACAGTATTCA
AGGTCAGTTAAATCAGCTCAAAGACTATTGTCAATTTCAAGGTTATGAAGTCGTTGATGAATATACCGATCGTGGTATAT
CGGGTAAAACAACACAACGTCCTGAATTACAACGTATGTTGAAAGATGCGAAAGAAAATAAATTAGACTGTATTATGGTC
TACAAAACCAATCGCTTAGCTAGAAATACGTCAGACTTATTAAGTATAGTAGAAAAATTGTATAAACTTAACGTAGAATT
TTTTAGTCTCACTGAAAAGATAGAAATTGCCACATCTACAGGTAAGTTAATGCTTCAAATTCTTGCTAGTTTCTCTGAAT
TCGAACGTAATACGATTGTAGAAAACGTTTATAACGGTCAAAGACAACGAGCGATTGAAGGATATTATCAAGGTAATTTA
CCTCTAGGCTATGACAAAATACCTGATAGTAAAAAAGAACTGATGATTAATCAACATGAAGCCCATATCGTCAAATATAT
TTTTGAGTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCGTTTAGTATTTCGTCCATTACCTACATCATCTCTAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAAGAACCGATTATCGCAGATGGTAAACATGCACCGATTATTGA
TAAAGCTTTATGGGATAAAGTACAGTTTAAACGCCAAGAGAGTCGCAAGAAACCACAAGTTCACGGTAAAGGGACAAACC
TACTGACTGGCATTGTAAAATGTCCAAAATGTGGTGCAGCAATGGCGGCAAGTAATACGACCAATACGTTAAAAGATGGC
ACTAAAAAAAGAATAAGATATTACTCATGTAGTAATTTTAGAAATAAAGGTTCTAAAGTTTGTTCAGCCAATAGTGTTAG
AGCAGATGTATTGGAAAAATATGTTATGGATCAAATATTGGAAATTATCAAAAGTAAAAAGGTATTGAAAAAATTGGTTG
AAAAGATAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTAAATCACGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCTAAAATGCATACACTAACGAAAACTATCGAAGACTCCCCTGACTTAGATAGTGTATTGAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCCATCAACTAAAACAAGATAAACAAGCGGAAGCTCTACATT
ATGATGCTGATATGATTGTTAATGTATTACAGGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
TTGTATCTGACGGTTATTGATCGTATTGATATCCGAAAACATGAGCATCATAAAAAACAATTTTATGTTACGCTCAAACT
AAATAATGAGATTATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTTTGC
CACAGACGCTATATCTTACTATTTAA
GTGAAAAATGTAAAGAAAAAACGTATTGGATTATACGCACGTGTATCGACTGAAATGCAAACGGATGGATACAGTATTCA
AGGTCAGTTAAATCAGCTCAAAGACTATTGTCAATTTCAAGGTTATGAAGTCGTTGATGAATATACCGATCGTGGTATAT
CGGGTAAAACAACACAACGTCCTGAATTACAACGTATGTTGAAAGATGCGAAAGAAAATAAATTAGACTGTATTATGGTC
TACAAAACCAATCGCTTAGCTAGAAATACGTCAGACTTATTAAGTATAGTAGAAAAATTGTATAAACTTAACGTAGAATT
TTTTAGTCTCACTGAAAAGATAGAAATTGCCACATCTACAGGTAAGTTAATGCTTCAAATTCTTGCTAGTTTCTCTGAAT
TCGAACGTAATACGATTGTAGAAAACGTTTATAACGGTCAAAGACAACGAGCGATTGAAGGATATTATCAAGGTAATTTA
CCTCTAGGCTATGACAAAATACCTGATAGTAAAAAAGAACTGATGATTAATCAACATGAAGCCCATATCGTCAAATATAT
TTTTGAGTCATACGCTAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCGTTTAGTATTTCGTCCATTACCTACATCATCTCTAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAAGAACCGATTATCGCAGATGGTAAACATGCACCGATTATTGA
TAAAGCTTTATGGGATAAAGTACAGTTTAAACGCCAAGAGAGTCGCAAGAAACCACAAGTTCACGGTAAAGGGACAAACC
TACTGACTGGCATTGTAAAATGTCCAAAATGTGGTGCAGCAATGGCGGCAAGTAATACGACCAATACGTTAAAAGATGGC
ACTAAAAAAAGAATAAGATATTACTCATGTAGTAATTTTAGAAATAAAGGTTCTAAAGTTTGTTCAGCCAATAGTGTTAG
AGCAGATGTATTGGAAAAATATGTTATGGATCAAATATTGGAAATTATCAAAAGTAAAAAGGTATTGAAAAAATTGGTTG
AAAAGATAAATGAAAAAAGTCAAATAGACGTCTCTTCTTTAAATCACGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCTAAAATGCATACACTAACGAAAACTATCGAAGACTCCCCTGACTTAGATAGTGTATTGAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATCCATCAACTAAAACAAGATAAACAAGCGGAAGCTCTACATT
ATGATGCTGATATGATTGTTAATGTATTACAGGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
TTGTATCTGACGGTTATTGATCGTATTGATATCCGAAAACATGAGCATCATAAAAAACAATTTTATGTTACGCTCAAACT
AAATAATGAGATTATCAAACAACTATTTAATAACCATCCACTCGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTTTGC
CACAGACGCTATATCTTACTATTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
73.247 |
100 |
0.734 |