Detailed information NTG0514656

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: KX728_RS07880
• Genome accession: NZ_CP079724
• Coordinates: 1625242..1627338 (-)
• Length: 698 a.a.
• NCBI ID: WP_215804332.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1620242..1632338

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS07850 (KX728_07845)	-	1620477..1621508 (-)	1032	WP_215804336.1	sensor histidine kinase KdpD	-
KX728_RS07855 (KX728_07850)	-	1621475..1622173 (-)	699	WP_215804335.1	response regulator transcription factor	-
KX728_RS07860 (KX728_07855)	-	1622186..1622908 (-)	723	Protein_1513	lantibiotic ABC transporter permease	-
KX728_RS07865 (KX728_07860)	-	1622908..1623696 (-)	789	WP_215804334.1	lantibiotic ABC transporter permease	-
KX728_RS07870 (KX728_07865)	-	1623698..1624405 (-)	708	WP_215804333.1	ABC transporter ATP-binding protein	-
KX728_RS07875 (KX728_07870)	-	1624701..1625183 (+)	483	WP_000032557.1	S-ribosylhomocysteine lyase	-
KX728_RS07880 (KX728_07875)	clpE	1625242..1627338 (-)	2097	WP_215804332.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
KX728_RS07885 (KX728_07880)	-	1627790..1631542 (-)	3753	WP_219108624.1	Spy0128 family protein	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77178.00 Da
• Isoelectric Point: 4.7685

>NTDB_id=514656 KX728_RS07880 WP_215804332.1 1625242..1627338(-) (clpE) [Streptococcus oralis strain 34]
MNNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAEVDGQMQQHASGMKQDGILAKLGRNL
TAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEAG
TQYRGSFEENVQNLINEVKEAGNIILFFDEIHQILGAGSIGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTILKN
AALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSIQYIPQRSLPDKAIDLVDVTAAHLAAQHP
VTDVHAVEREIEAEKDKQEKAVEAEDFEAALNAKTRIAELEKKVANHTEDMKVTASINDVAESVERMTGIPVSQMGASDI
ERLKDMAHRLEHKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMSE
YSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVII
ATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLNKEDLSKIVDLMLEEVNQTLAKKDIDLEVSQAA
KDFITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKA

Nucleotide

• Length: 2097 bp

>NTDB_id=514656 KX728_RS07880 WP_215804332.1 1625242..1627338(-) (clpE) [Streptococcus oralis strain 34]
ATGAACAACAACTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTCTGAAAATCG
TCGCTACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGCCAGGAAATG
CAGAAGTTGATGGACAAATGCAACAACACGCTTCAGGTATGAAACAAGACGGTATCCTTGCTAAACTAGGTCGTAACTTG
ACAGCGGAAGCTCGTGAGGGCAAGTTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAACATCTGAAATCCTCTC
ACGTCGTACGAAAAATAATCCTGTTCTAGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGTCTAGCACAAG
CGATTGTGAATGGAGATGTTCCGGCTGCCATTAAGAACAAGGAAATTATTTCTATTGATATCTCAGGTCTTGAGGCTGGT
ACTCAATACCGTGGTAGCTTTGAAGAAAACGTTCAAAATCTAATCAATGAAGTAAAAGAAGCAGGGAATATTATCCTCTT
CTTTGATGAAATTCACCAAATCCTTGGCGCTGGCTCAATCGGAGGTGATAGTGGTTCTAAAGGTCTTGCGGATATTCTCA
AGCCAGCTCTCTCTCGTGGTGAGTTGACAGTGATTGGGGCAACGACTCAAGATGAATACCGTAACACCATCTTGAAAAAT
GCAGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCAGCAGAGGATACCTTTAAAATCCTTCAAGGGAT
TCGTGACCTCTATCAACAACATCACAATGTTATCTTGCCAGACGAGGTCTTGAAGGCAGCAGTGGATTATTCGATCCAAT
ACATTCCTCAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACGGCAGCTCACTTGGCAGCTCAACATCCT
GTAACAGATGTGCATGCTGTTGAACGGGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGCAGAAGACTT
TGAAGCAGCTCTCAATGCCAAAACACGCATTGCTGAATTAGAGAAAAAAGTCGCAAACCACACAGAAGACATGAAAGTGA
CTGCAAGCATCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATTCCAGTGTCACAAATGGGAGCATCAGATATC
GAACGTTTGAAAGATATGGCTCATCGCTTGGAACACAAGGTAATTGGCCAAGATAAGGCAGTAGAAGCAGTAGCTCGTGC
TATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGTCCAACTGGGGTTG
GTAAGACCGAGCTTGCTAAGCAATTGGCACTGGATATGTTTGGAACTAAGGATGCTATCATTCGTTTGGATATGTCTGAA
TACAGTGACCGCACAGCTGTATCTAAGTTGATCGGTACAACAGCTGGTTATGTGGGGTATGATGACAATAGCAATACCTT
GACAGAACGTGTTCGTCGTAATCCTTACTCTATCATTCTCTTGGATGAGATTGAAAAGGCTGATCCTCAAGTCATTACCC
TTCTCCTCCAAGTCTTGGATGATGGTCGTTTAACTGATGGTCAAGGAAATACAGTGAACTTCAAGAACACTGTCATTATC
GCAACATCAAATGCTGGATTTGGCTATGAAGCCAACTTGACTGAAGATGCGGATAAACCAGAGTTGATGGATCGTTTGAA
ACCATTCTTCCGTCCAGAGTTCCTTAACCGCTTTAACGCAGTTATCGAGTTCTCACACTTGAATAAGGAAGACCTTTCTA
AGATTGTGGACTTAATGTTGGAGGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTGGAAGTTAGTCAAGCAGCT
AAGGACTTTATCACAGAAGAAGGTTATGACGAAGTTATGGGTGTTCGTCCTCTCCGTCGCGTGGTTGAACAACAAATTCG
TGATAAGGTGACAGATTTCCACTTGGATCATCTAGATGCCAAACATCTGGAAGCAGATATGGAAGATGGCGTTTTGGTCA
TTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-677)

• ATPase family associated with various cellular activities (AAA) (AAA) (115-247)

• AAA lid domain (AAA_lid_9) (256-351)

• AAA domain (Cdc48 subfamily) (AAA_2) (440-600)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	50.621	92.264	0.467
clpC	Lactococcus lactis subsp. cremoris KW2	50	91.691	0.458
clpE	Streptococcus pneumoniae TIGR4	48.738	90.831	0.443
clpE	Streptococcus pneumoniae Rx1	48.428	91.117	0.441
clpE	Streptococcus pneumoniae D39	48.428	91.117	0.441
clpE	Streptococcus pneumoniae R6	48.428	91.117	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	44.87	93.553	0.42
clpC	Streptococcus pneumoniae D39	43.77	89.685	0.393
clpC	Streptococcus pneumoniae Rx1	43.77	89.685	0.393
clpC	Streptococcus pneumoniae TIGR4	43.61	89.685	0.391
clpC	Streptococcus thermophilus LMD-9	43.134	88.682	0.383
clpC	Streptococcus thermophilus LMG 18311	42.973	88.682	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.626	88.395	0.377
clpC	Streptococcus mutans UA159	42.071	88.539	0.372