Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   KX728_RS04685 Genome accession   NZ_CP079724
Coordinates   944664..945128 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus oralis strain 34     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 939664..950128
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS04660 (KX728_04655) - 940447..942216 (+) 1770 WP_042902253.1 DUF262 domain-containing protein -
  KX728_RS04665 (KX728_04660) - 942252..942830 (+) 579 WP_042902254.1 hypothetical protein -
  KX728_RS04670 (KX728_04665) - 942872..943564 (+) 693 WP_042902255.1 YjjG family noncanonical pyrimidine nucleotidase -
  KX728_RS04675 (KX728_04670) - 943588..943881 (+) 294 WP_042902256.1 hypothetical protein -
  KX728_RS04680 (KX728_04675) - 944001..944654 (+) 654 WP_215804687.1 uracil-DNA glycosylase -
  KX728_RS04685 (KX728_04680) mutX 944664..945128 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  KX728_RS04690 (KX728_04685) - 945141..946409 (+) 1269 WP_215804686.1 dihydroorotase -
  KX728_RS04695 (KX728_04690) - 946451..947791 (+) 1341 WP_084921863.1 MATE family efflux transporter -
  KX728_RS04700 (KX728_04695) - 947970..948938 (+) 969 WP_000105349.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  KX728_RS04705 (KX728_04700) - 948955..949947 (+) 993 WP_033681771.1 alpha-ketoacid dehydrogenase subunit beta -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=514624 KX728_RS04685 WP_001135768.1 944664..945128(+) (mutX) [Streptococcus oralis strain 34]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=514624 KX728_RS04685 WP_001135768.1 944664..945128(+) (mutX) [Streptococcus oralis strain 34]
ATGCCTCAGTTAGCGACTATTTGCTACATTGATAACGGAAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCACGAAGGCAAATGGATTGGTGTGGGTGGTAAGCTAGAGCGAGGGGAGACACCTCAGGAGTGCGCAGCGCGTGAAA
TCCTCGAAGAAACAGGCCTCAAAGCCAAGCCAGTACTTAAAGGTGTTATCACTTTTCCAGAATTCACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACAGAGTTTGAGGGTGACTTGATTGACTGCAATGAGGGGACGCTGGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCAACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGACAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTATTGGATACCCAAGTCGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987