Detailed information NTG0051444

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLNZ_RS12240
• Genome accession: NC_017949
• Coordinates: 2394653..2395684 (-)
• Length: 343 a.a.
• NCBI ID: WP_011836077.1
• Uniprot ID: A0A084AC41
• Organism: Lactococcus cremoris subsp. cremoris NZ9000
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2389653..2400684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLNZ_RS14020	-	2389762..2390607 (-)	846	WP_242700777.1	radical SAM protein	-
LLNZ_RS12225 (LLNZ_12605)	-	2390791..2391648 (-)	858	WP_011836073.1	Rgg/GadR/MutR family transcriptional regulator	-
LLNZ_RS12230 (LLNZ_12610)	-	2391700..2392836 (-)	1137	WP_011836074.1	MFS transporter	-
LLNZ_RS12235 (LLNZ_12615)	kwcM	2392833..2394152 (-)	1320	WP_011836075.1	KxxxW cyclic peptide radical SAM maturase	-
LLNZ_RS13315 (LLNZ_12620)	-	2394220..2394333 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLNZ_RS12240 (LLNZ_12625)	sepM	2394653..2395684 (-)	1032	WP_011836077.1	SepM family pheromone-processing serine protease	Regulator
LLNZ_RS12245 (LLNZ_12630)	coaD	2395668..2396168 (-)	501	WP_011836078.1	pantetheine-phosphate adenylyltransferase	-
LLNZ_RS12250 (LLNZ_12635)	rsmD	2396216..2396755 (-)	540	WP_011836079.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLNZ_RS12255 (LLNZ_12640)	-	2396928..2398145 (-)	1218	WP_011836080.1	MFS transporter	-
LLNZ_RS12260 (LLNZ_12645)	lmrP	2398230..2399456 (-)	1227	WP_011836081.1	multidrug efflux MFS transporter LmrP	-
LLNZ_RS12265 (LLNZ_12650)	-	2399691..2400134 (+)	444	WP_041931231.1	sigma-70 family RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37403.02 Da
• Isoelectric Point: 9.9119

>NTDB_id=51444 LLNZ_RS12240 WP_011836077.1 2394653..2395684(-) (sepM) [Lactococcus cremoris subsp. cremoris NZ9000]
MNKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKISNGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGMMFTLEIYSQLTGKNLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALTYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=51444 LLNZ_RS12240 WP_011836077.1 2394653..2395684(-) (sepM) [Lactococcus cremoris subsp. cremoris NZ9000]
ATGAACAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGCCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGGAAAATGGTCAAAGTTGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGTGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGTCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACTGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGCAGTAAACACAAGTCTACTGGAAAATATATCAAAATCTCTAATGGAAAAACCGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATGATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAAATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAACTTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A084AC41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.406	100	0.487