Detailed information NTG0514017

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: KV188_RS00830
• Genome accession: NZ_CP078508
• Coordinates: 170891..173719 (-)
• Length: 942 a.a.
• NCBI ID: WP_005601043.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae serovar 8 str. 405
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 165891..178719

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV188_RS00810 (KV188_00810)	-	167374..168060 (-)	687	WP_005601038.1	CidB/LrgB family autolysis modulator	-
KV188_RS00815 (KV188_00815)	-	168070..168429 (-)	360	WP_005601040.1	CidA/LrgA family protein	-
KV188_RS00820 (KV188_00820)	-	168496..170418 (-)	1923	WP_005607710.1	ATP-dependent DNA helicase	-
KV188_RS00825 (KV188_00825)	-	170540..170752 (+)	213	WP_005597221.1	hypothetical protein	-
KV188_RS00830 (KV188_00830)	uvrA	170891..173719 (-)	2829	WP_005601043.1	excinuclease ABC subunit UvrA	Machinery gene
KV188_RS00835 (KV188_00835)	ssb	173870..174394 (+)	525	WP_039195080.1	single-stranded DNA-binding protein	Machinery gene
KV188_RS00840 (KV188_00840)	-	174604..175503 (-)	900	WP_039709098.1	LysR family transcriptional regulator	-
KV188_RS00845 (KV188_00845)	-	175615..176604 (+)	990	WP_058230472.1	zinc-dependent alcohol dehydrogenase family protein	-
KV188_RS00850 (KV188_00850)	-	176688..177086 (-)	399	WP_010907411.1	Cd(II)/Pb(II)-responsive transcriptional regulator	-
KV188_RS00855 (KV188_00855)	-	177158..177772 (+)	615	WP_010907412.1	cation diffusion facilitator family transporter	-

Sequence

Protein

• Length: 942 a.a.
• Molecular weight: 104424.85 Da
• Isoelectric Point: 6.5783

>NTDB_id=514017 KV188_RS00830 WP_005601043.1 170891..173719(-) (uvrA) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
MQYIDVRGARTHNLKNINLILPRDKFIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTVTEIHDYLRLLFARVGEPRCPDHDLPLAAQTISQMVDRVMEEPEGKRLMLLAPVVKNRKG
EHVKLLENLTASGYIRARIDGEICDLSDPPTLELQKKHTIEVVVDRFKVRSDIATRLAESFETALDLSGSTAIIADMDDP
NAEEIVFSSSFACPHCGYSLHELEPRLFSFNNPAGACPTCDGLGVEQYFDPNKVVQNPDVSLASGAIKGWDRRSFYYFGL
LKSVADHYDFSLDTPFKDLTKKQRDIILNGSKDEIEFVYVNDRGDKVKRKHTFEGVLNNMARRYKETESNSVREELAKYI
NSRPCLECEGSRLRREARYVFLDKTNLPMVSEKSIGEALEFFEQLDLAGQKAKIAEKILKEIRERLQFLVNVGLNYLSLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLIHLRNLGNTVIVVEHDEDAIRAADHIVDIG
PGAGVHGGQVIAQGTAEEIMQVEDSITGQFLSGKQKIEIPAKRVSYDAAKLLTLKGASGNNLKQVQLDIPVGLFTCITGV
SGSGKSTLINDTLFPLAQNALNRAERTDVAPYESIDGLSHFDKVIDIDQSPIGRTPRSNPATYTGLFTPIRELFAGTQEA
RARGYNVGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDHCKGKRYNRETLEIRYKGKTIHQVLDMTVEEAREFFA
PVPAIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYILDEPTTGLHFADIKQLLSVLHKLRDQ
GNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGQIIATGTPEEVAKDKRSHTARFLKEILAKG

Nucleotide

• Length: 2829 bp

>NTDB_id=514017 KV188_RS00830 WP_005601043.1 170891..173719(-) (uvrA) [Actinobacillus pleuropneumoniae serovar 8 str. 405]
ATGCAGTACATTGATGTTCGTGGTGCGCGAACCCACAACCTTAAAAATATCAATTTAATTCTTCCTCGAGATAAATTTAT
TGTAATTACCGGCTTATCCGGATCGGGTAAGTCTTCTTTAGCTTTCGATACGCTGTATGCGGAAGGGCAACGCCGTTATG
TGGAATCGCTTTCCGCTTATGCACGCCAATTCCTTTCATTGATGGAAAAACCGGATGTGGACCATATCGAAGGGCTTTCG
CCGGCGATTTCTATCGAGCAAAAATCCACCTCGCATAACCCTCGTTCTACGGTGGGGACGGTAACTGAAATCCACGACTA
TTTACGTCTGTTGTTCGCTCGTGTCGGTGAGCCTCGTTGTCCGGATCACGATTTGCCGCTGGCGGCACAAACCATTTCGC
AGATGGTGGATAGAGTAATGGAAGAGCCGGAAGGCAAGCGTTTGATGCTACTTGCGCCGGTGGTTAAAAATCGTAAAGGC
GAACACGTAAAATTATTGGAAAATTTGACCGCTTCCGGTTATATCCGAGCCAGAATTGACGGCGAAATCTGTGATTTATC
TGATCCGCCGACATTGGAATTACAGAAAAAGCATACGATTGAAGTGGTGGTCGATCGCTTTAAAGTGAGAAGTGATATTG
CCACACGTTTAGCGGAATCTTTTGAAACGGCATTGGATTTATCTGGTTCGACCGCAATTATTGCCGATATGGATGATCCG
AATGCGGAAGAAATCGTCTTTTCGTCTAGTTTTGCTTGTCCGCATTGCGGCTATTCGCTACACGAATTAGAGCCTCGTTT
GTTCTCATTTAATAACCCAGCCGGTGCTTGCCCGACGTGTGACGGCTTAGGGGTAGAGCAGTATTTTGACCCGAATAAAG
TAGTACAAAATCCGGATGTCTCGTTAGCAAGCGGTGCGATTAAAGGTTGGGATCGCCGTAGCTTTTACTATTTCGGTTTG
TTGAAATCGGTGGCGGATCATTATGATTTTTCACTGGATACGCCGTTTAAAGATCTGACTAAAAAACAACGTGACATTAT
TCTGAACGGTTCAAAAGACGAAATCGAATTTGTTTATGTCAATGATCGCGGCGATAAAGTAAAACGTAAACATACCTTTG
AAGGTGTGTTAAATAATATGGCTCGCCGTTATAAAGAAACCGAGTCGAATTCGGTGCGTGAAGAATTAGCGAAATATATC
AATAGCCGCCCGTGTTTAGAGTGTGAAGGATCTCGCTTACGTCGTGAGGCACGTTATGTCTTTTTAGATAAAACCAATTT
GCCGATGGTGTCGGAAAAATCGATTGGCGAAGCGTTAGAATTTTTTGAACAGTTAGATCTTGCCGGTCAAAAAGCGAAGA
TTGCGGAGAAAATTTTAAAAGAAATTCGTGAACGTTTGCAGTTCTTGGTCAATGTCGGCTTGAATTACCTCTCGCTTTCT
CGTTCGGCGGAAACCTTATCCGGCGGTGAGGCGCAACGTATCCGTTTAGCCAGCCAAATCGGTGCAGGCTTGGTTGGGGT
GATGTATGTGCTGGATGAGCCGTCTATCGGATTGCACCAACGTGATAACGAACGTTTATTAAATACCTTAATTCATCTGC
GTAATTTGGGTAATACCGTAATTGTGGTGGAGCATGATGAAGATGCGATCCGTGCCGCAGATCATATTGTCGATATCGGC
CCGGGAGCCGGTGTGCACGGTGGCCAAGTTATTGCACAAGGTACAGCGGAAGAAATTATGCAGGTGGAAGATTCGATTAC
CGGACAATTCCTCTCCGGCAAGCAGAAGATTGAAATTCCGGCAAAACGAGTGTCTTATGACGCGGCTAAATTGCTAACCT
TAAAAGGGGCAAGCGGTAATAACTTAAAACAAGTACAGTTGGATATTCCGGTTGGTTTATTCACTTGTATTACCGGTGTC
TCGGGTTCGGGTAAATCGACTCTAATCAACGATACCTTGTTCCCATTAGCACAAAATGCGTTAAATCGTGCGGAACGTAC
CGATGTCGCACCTTATGAGTCAATTGACGGCTTATCGCATTTCGATAAAGTGATTGATATCGACCAAAGCCCGATTGGGC
GTACACCACGTTCAAACCCGGCAACCTATACCGGTTTATTTACGCCGATTCGTGAATTATTTGCCGGTACGCAAGAAGCG
AGAGCGAGAGGCTATAATGTCGGACGCTTTAGTTTTAATGTGCGTGGCGGACGTTGTGAAGCCTGTCAAGGCGATGGCGT
GATTAAAGTGGAAATGCACTTCCTACCGGATGTATATGTGCCGTGTGATCATTGCAAAGGTAAACGTTATAACCGAGAAA
CTTTGGAAATCCGTTATAAAGGCAAAACGATTCATCAAGTGTTGGATATGACGGTGGAAGAAGCGAGAGAATTTTTCGCA
CCGGTACCGGCGATTGCGCGTAAATTGCAAACCTTAATGGATGTCGGTTTATCGTATATTCGCTTAGGACAGTCCTCGAC
CACGCTTTCCGGCGGTGAAGCGCAGCGTGTTAAATTAGCGACCGAGCTTTCCAAACGTGATACCGGCAAAACGCTGTATA
TCTTAGACGAACCGACCACCGGTTTACATTTTGCCGATATTAAACAGCTACTTTCGGTGTTACACAAATTGCGTGACCAA
GGTAATACGATTGTGGTGATCGAGCATAATTTAGATGTGATTAAAACCGCCGACTGGATTGTGGACTTAGGCCCTGAAGG
CGGTTCGGGCGGCGGACAAATTATTGCGACCGGCACACCGGAAGAGGTAGCGAAAGACAAACGCTCGCACACGGCAAGAT
TTTTAAAAGAGATCTTAGCTAAAGGGTAA

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-237)

• UvrA DNA-binding domain (UvrA_DNA-bind) (290-398)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	56.823	99.575	0.566
uvrA	Streptococcus pneumoniae TIGR4	56.823	99.575	0.566
uvrA	Streptococcus pneumoniae D39	56.823	99.575	0.566