Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   I6G22_RS06970 Genome accession   NZ_CP065737
Coordinates   1305260..1306288 (+) Length   342 a.a.
NCBI ID   WP_023190255.1    Uniprot ID   A0AAW7IXD6
Organism   Lactococcus lactis strain FDAARGOS_865     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1300260..1311288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G22_RS06950 (I6G22_06955) lmrP 1301490..1302716 (+) 1227 WP_025017145.1 multidrug efflux MFS transporter LmrP -
  I6G22_RS06955 (I6G22_06960) - 1302798..1304018 (+) 1221 WP_003132654.1 MDR family MFS transporter -
  I6G22_RS06960 (I6G22_06965) rsmD 1304189..1304728 (+) 540 WP_023190253.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6G22_RS06965 (I6G22_06970) coaD 1304776..1305273 (+) 498 WP_025017143.1 pantetheine-phosphate adenylyltransferase -
  I6G22_RS06970 (I6G22_06975) sepM 1305260..1306288 (+) 1029 WP_023190255.1 SepM family pheromone-processing serine protease Regulator
  I6G22_RS06975 (I6G22_06980) - 1306610..1306723 (+) 114 WP_011836076.1 KxxxW-cyclized peptide pheromone -
  I6G22_RS06980 (I6G22_06985) kwcM 1306791..1308110 (+) 1320 WP_025017142.1 KxxxW cyclic peptide radical SAM maturase -
  I6G22_RS06985 (I6G22_06990) - 1308107..1309246 (+) 1140 WP_044009594.1 MFS transporter -
  I6G22_RS06990 (I6G22_06995) - 1309357..1310214 (+) 858 WP_023190258.1 Rgg/GadR/MutR family transcriptional regulator -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37296.91 Da        Isoelectric Point: 9.8043

>NTDB_id=513726 I6G22_RS06970 WP_023190255.1 1305260..1306288(+) (sepM) [Lactococcus lactis strain FDAARGOS_865]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGCEIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=513726 I6G22_RS06970 WP_023190255.1 1305260..1306288(+) (sepM) [Lactococcus lactis strain FDAARGOS_865]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGTAAAACAGGAATTGGGA
TTAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCGAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTTGCGAAATTGCTGGAACTGG
GACGATTGAACACGACGGAAGCATTGGTCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGTAAAGAAGGGGCAA
AAGTCTTCTTAGTGCCTGATTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.406

100

0.488