Detailed information NTG0513622

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: KWZ00_RS07680
• Genome accession: NZ_CP078115
• Coordinates: 1458436..1459662 (-)
• Length: 408 a.a.
• NCBI ID: WP_047918752.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain O1G1370
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1453436..1464662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KWZ00_RS07670 (KWZ00_07670)	-	1455401..1455685 (+)	285	WP_047918726.1	GIY-YIG nuclease family protein	-
KWZ00_RS07675 (KWZ00_07675)	yccS	1456169..1458319 (-)	2151	WP_003697785.1	YccS family putative transporter	-
KWZ00_RS07680 (KWZ00_07680)	pilU	1458436..1459662 (-)	1227	WP_047918752.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
KWZ00_RS07685 (KWZ00_07685)	pilT	1459826..1460869 (-)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
KWZ00_RS07690 (KWZ00_07690)	-	1460989..1461675 (+)	687	WP_218422837.1	YggS family pyridoxal phosphate-dependent enzyme	-
KWZ00_RS07695 (KWZ00_07695)	-	1461675..1462082 (+)	408	WP_003690202.1	hypothetical protein	-
KWZ00_RS07700 (KWZ00_07700)	proC	1462131..1462922 (+)	792	WP_003690203.1	pyrroline-5-carboxylate reductase	-
KWZ00_RS07705 (KWZ00_07705)	dksA	1463070..1463486 (+)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
KWZ00_RS12040	-	1463501..1463629 (+)	129	WP_256204576.1	hypothetical protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45642.26 Da
• Isoelectric Point: 7.3203

>NTDB_id=513622 KWZ00_RS07680 WP_047918752.1 1458436..1459662(-) (pilU) [Neisseria gonorrhoeae strain O1G1370]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGAHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=513622 KWZ00_RS07680 WP_047918752.1 1458436..1459662(-) (pilU) [Neisseria gonorrhoeae strain O1G1370]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCGCACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387