Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   I6G28_RS00510 Genome accession   NZ_CP065726
Coordinates   89947..91371 (-) Length   474 a.a.
NCBI ID   WP_111727510.1    Uniprot ID   A0A7T3BLV7
Organism   Neisseria cinerea strain FDAARGOS_871     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 84947..96371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G28_RS00485 (I6G28_00485) yccS 85403..87553 (+) 2151 WP_111727512.1 YccS family putative transporter -
  I6G28_RS09245 - 87573..87695 (+) 123 WP_003678392.1 hypothetical protein -
  I6G28_RS09250 (I6G28_00490) - 87692..88315 (-) 624 WP_269460473.1 pilin -
  I6G28_RS00495 (I6G28_00495) pilA2 88356..88832 (-) 477 WP_108044216.1 pilin Machinery gene
  I6G28_RS00500 (I6G28_00500) - 88900..89160 (-) 261 WP_111727511.1 hypothetical protein -
  I6G28_RS00505 (I6G28_00505) - 89370..89636 (-) 267 WP_019271767.1 DUF3079 domain-containing protein -
  I6G28_RS00510 (I6G28_00510) pilA 89947..91371 (-) 1425 WP_111727510.1 signal recognition particle-docking protein FtsY Machinery gene
  I6G28_RS00515 (I6G28_00515) msrAB 91517..93085 (+) 1569 WP_111727509.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  I6G28_RS00520 (I6G28_00520) - 93170..93655 (-) 486 WP_111727508.1 CinA family protein -
  I6G28_RS00525 (I6G28_00525) - 93686..94687 (-) 1002 WP_111727507.1 thiamine ABC transporter substrate-binding protein -
  I6G28_RS00530 (I6G28_00530) - 94746..95426 (+) 681 WP_111727506.1 pyrimidine 5'-nucleotidase -
  I6G28_RS00535 (I6G28_00535) - 95452..95724 (+) 273 WP_111727505.1 membrane lipoprotein lipid attachment site-containing protein -

Sequence

Protein


Download         Length: 474 a.a.        Molecular weight: 50906.56 Da        Isoelectric Point: 4.3031

>NTDB_id=513567 I6G28_RS00510 WP_111727510.1 89947..91371(-) (pilA) [Neisseria cinerea strain FDAARGOS_871]
MFSFFRRKKKQETPAPEEAQVQETAAKIESEVAQVIENIKEDSESLAESVKGNVESVVESAVETVSETVSETVEQVREAL
TETLSETVEKVEEHVEAAKEAAVETASEALEQVKETVAEMPSEVAEAAEEAVEQAEAVKEEAVEAVSEAVEPVQEAVAET
PAEASAPAEEHKLSWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELETVLITSDMGMEATEYLMKDVRDRVSLKG
LKDGNELRGALKDALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQ
LQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEIKKVKRVLQKAMPDAPHEIIVVLD
ANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1425 bp        

>NTDB_id=513567 I6G28_RS00510 WP_111727510.1 89947..91371(-) (pilA) [Neisseria cinerea strain FDAARGOS_871]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACTCCGGCTCCTGAGGAGGCTCAAGTTCAGGAAACCGCAGCAAA
AATAGAATCTGAAGTTGCTCAAGTAATTGAAAATATTAAAGAAGATTCCGAATCTTTAGCAGAAAGCGTCAAAGGGAATG
TTGAATCAGTTGTCGAATCGGCTGTTGAAACTGTCAGCGAAACCGTCAGCGAAACCGTCGAGCAGGTTCGGGAAGCTTTG
ACCGAAACGCTGTCTGAAACAGTCGAAAAAGTAGAAGAACACGTTGAAGCGGCAAAAGAAGCGGCTGTTGAAACCGCCAG
CGAGGCTCTTGAACAGGTAAAAGAAACCGTTGCCGAGATGCCGTCTGAAGTGGCTGAAGCTGCTGAGGAAGCAGTAGAAC
AGGCCGAAGCAGTCAAAGAAGAAGCTGTTGAGGCAGTTAGCGAAGCTGTCGAGCCAGTTCAAGAAGCCGTTGCGGAAACA
CCGGCTGAAGCCTCTGCTCCGGCAGAAGAACATAAGCTCAGTTGGGCGGCGCGTTTGAAACAAGGCTTGACCAAATCACG
CGACAAAATGGCAAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAGATCGACGAGGATTTGTACGAAGAGCTGGAAACCG
TGTTGATTACCAGCGACATGGGCATGGAAGCGACGGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGG
CTGAAAGACGGCAACGAATTGCGCGGCGCGCTGAAGGATGCGCTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGT
CTTGCCCGAAACCAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAAC
TCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCAGCCGCGCGTGAGCAG
CTTCAGGCTTGGGGAGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCAGCCGTTTGTTTTGATGC
CGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGA
TGGAAGAAATCAAAAAAGTGAAGCGCGTACTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGAT
GCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATCGTTACCAA
GCTAGACGGCACGGCAAAAGGCGGCATCCTTGCCGCGCTTGCCTCCGACCGCCCAGTTCCTGTCCGCTACATCGGCGTAG
GCGAAGGCATAGACGATTTGCGTCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(189-255)

SRP54-type protein, GTPase domain (SRP54)

(274-473)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3BLV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

79.536

100

0.795