Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   Y1U_RS08870 Genome accession   NC_017927
Coordinates   1698645..1699586 (-) Length   313 a.a.
NCBI ID   WP_014727726.1    Uniprot ID   -
Organism   Streptococcus thermophilus MN-ZLW-002     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1693645..1704586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Y1U_RS08830 (Y1U_C1742) - 1693721..1694914 (-) 1194 WP_014608740.1 acetate kinase -
  Y1U_RS08835 (Y1U_C1743) comYH 1694970..1695926 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  Y1U_RS08840 (Y1U_C1744) comGG 1695971..1696288 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG -
  Y1U_RS08845 (Y1U_C1745) comYF 1696266..1696703 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  Y1U_RS08850 comGE 1696687..1696980 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  Y1U_RS08855 (Y1U_C1747) comYD 1696952..1697380 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  Y1U_RS08860 (Y1U_C1748) comYC 1697340..1697666 (-) 327 WP_014727724.1 competence type IV pilus major pilin ComGC Machinery gene
  Y1U_RS08865 (Y1U_C1749) comYB 1697663..1698763 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  Y1U_RS08870 (Y1U_C1750) comGA/cglA/cilD 1698645..1699586 (-) 942 WP_014727726.1 competence type IV pilus ATPase ComGA Machinery gene
  Y1U_RS08875 (Y1U_C1751) - 1699667..1700029 (-) 363 WP_014608746.1 DUF1033 family protein -
  Y1U_RS08880 (Y1U_C1752) rpoC 1700188..1703826 (-) 3639 WP_011681690.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35524.70 Da        Isoelectric Point: 6.6091

>NTDB_id=51356 Y1U_RS08870 WP_014727726.1 1698645..1699586(-) (comGA/cglA/cilD) [Streptococcus thermophilus MN-ZLW-002]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVARMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGISYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=51356 Y1U_RS08870 WP_014727726.1 1698645..1699586(-) (comGA/cglA/cilD) [Streptococcus thermophilus MN-ZLW-002]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGAGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTTCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

50.804

99.361

0.505
  comGA Latilactobacillus sakei subsp. sakei 23K

38.158

97.125

0.371

Multiple sequence alignment