Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6G42_RS00530 Genome accession   NZ_CP065707
Coordinates   118847..119671 (-) Length   274 a.a.
NCBI ID   WP_038804570.1    Uniprot ID   A0A7T2ZWS1
Organism   Streptococcus oralis strain FDAARGOS_885     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 113847..124671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G42_RS00515 (I6G42_00515) amiA 114870..116849 (-) 1980 WP_038804568.1 peptide ABC transporter substrate-binding protein Regulator
  I6G42_RS00525 (I6G42_00525) - 117375..118706 (-) 1332 WP_038804569.1 hemolysin family protein -
  I6G42_RS00530 (I6G42_00530) endA 118847..119671 (-) 825 WP_038804570.1 DNA/RNA non-specific endonuclease Machinery gene
  I6G42_RS00535 (I6G42_00535) - 119712..119903 (-) 192 WP_000791880.1 DNA-directed RNA polymerase subunit beta -
  I6G42_RS00540 (I6G42_00540) murA 119893..121173 (-) 1281 WP_038804571.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6G42_RS00545 (I6G42_00545) - 121196..121426 (-) 231 WP_080563327.1 DUF1146 family protein -
  I6G42_RS00550 (I6G42_00550) sepM 121482..122519 (-) 1038 WP_038804572.1 SepM family pheromone-processing serine protease Regulator
  I6G42_RS00555 (I6G42_00555) coaD 122503..122991 (-) 489 WP_038804573.1 pantetheine-phosphate adenylyltransferase -
  I6G42_RS00560 (I6G42_00560) rsmD 122981..123520 (-) 540 WP_038804574.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6G42_RS00565 (I6G42_00565) asnA 123585..124577 (-) 993 WP_038804575.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30045.73 Da        Isoelectric Point: 9.9038

>NTDB_id=513256 I6G42_RS00530 WP_038804570.1 118847..119671(-) (endA) [Streptococcus oralis strain FDAARGOS_885]
MNKKTRQALIGLLIFLLLSAGSYYIKQMQLTSNTPKTKVSQKKQASEAPSQELAESVLTESIKNQIKGDLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKPVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTN

Nucleotide


Download         Length: 825 bp        

>NTDB_id=513256 I6G42_RS00530 WP_038804570.1 118847..119671(-) (endA) [Streptococcus oralis strain FDAARGOS_885]
ATGAACAAAAAAACGAGACAGGCTCTGATAGGGCTACTCATATTCTTACTATTATCTGCTGGTAGCTATTATATCAAGCA
GATGCAGTTGACATCAAACACGCCTAAAACCAAAGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCTAGTCAGGAGTTGG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAACCAAATCAAGGGTGATCTCGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCTAGCAAACCCTATGCGGATAATAAAACAAAACCAGTCGGGAAAGA
GACAGTCCCAACTGTTGCCAATGCCATCTTATCCAAAGCCACTCGTCAGTATAAGAATCGTGAAGAGACTGGAAATGGAT
CTACCTCTTGGACGCCACCAGGGTGGCATCAGGTCAAGAATCTAAAGGGGACCTATACACATGCAGTTGACAGAGGACAC
CTGCTGGGCTATGCCTTAATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCGAATCAAGCGCAAGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AGAATAAGAGAGTCCGTTATCGGGTGACGCTTCACTATGCGACAAATGAGGATCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCGGATGGTGAATTGGAATTCAATGTCCTGATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGTCAAGTCACAGTGACAAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T2ZWS1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.377

99.635

0.891
  endA Streptococcus pneumoniae D39

89.377

99.635

0.891
  endA Streptococcus pneumoniae R6

89.377

99.635

0.891
  endA Streptococcus pneumoniae TIGR4

89.377

99.635

0.891