Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   I6G70_RS10365 Genome accession   NZ_CP065656
Coordinates   2152304..2153932 (+) Length   542 a.a.
NCBI ID   WP_011082534.1    Uniprot ID   Q8CQJ7
Organism   Staphylococcus epidermidis strain FDAARGOS_913     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2118983..2153911 2152304..2153932 flank -1607


Gene organization within MGE regions


Location: 2118983..2153932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G70_RS10195 (I6G70_10195) - 2120575..2122983 (-) 2409 WP_002485759.1 heavy metal translocating P-type ATPase -
  I6G70_RS10200 (I6G70_10200) - 2123240..2123935 (-) 696 WP_225793074.1 ZIP family metal transporter -
  I6G70_RS10205 (I6G70_10205) - 2124261..2124662 (-) 402 WP_002485756.1 ArsR/SmtB family transcription factor -
  I6G70_RS10210 (I6G70_10210) lspA 2124897..2125274 (+) 378 WP_011082547.1 signal peptidase II -
  I6G70_RS10215 (I6G70_10215) - 2125302..2125976 (-) 675 WP_011082546.1 IS6-like element IS257 family transposase -
  I6G70_RS10220 (I6G70_10220) - 2126001..2126225 (-) 225 WP_070866987.1 hypothetical protein -
  I6G70_RS10225 (I6G70_10225) - 2126408..2127565 (-) 1158 WP_002485721.1 hypothetical protein -
  I6G70_RS10230 (I6G70_10230) - 2127610..2128179 (-) 570 WP_002470562.1 hypothetical protein -
  I6G70_RS10235 (I6G70_10235) - 2128300..2129250 (+) 951 Protein_1982 transposase -
  I6G70_RS10240 (I6G70_10240) - 2130373..2132298 (-) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -
  I6G70_RS10245 (I6G70_10245) - 2132628..2132954 (-) 327 WP_000391495.1 ArsR/SmtB family transcription factor -
  I6G70_RS10250 (I6G70_10250) - 2133161..2133520 (+) 360 WP_001631039.1 hypothetical protein -
  I6G70_RS10255 (I6G70_10255) - 2133632..2133970 (-) 339 Protein_1986 recombinase family protein -
  I6G70_RS10260 (I6G70_10260) - 2133979..2134608 (+) 630 Protein_1987 hypothetical protein -
  I6G70_RS10265 (I6G70_10265) ccrA 2134795..2136156 (+) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  I6G70_RS10270 (I6G70_10270) ccrB 2136153..2137781 (+) 1629 WP_011082541.1 cassette chromosome recombinase CcrB Machinery gene
  I6G70_RS10275 (I6G70_10275) - 2138282..2138632 (+) 351 WP_002485722.1 SAUGI family uracil-DNA glycosylase inhibitor -
  I6G70_RS10280 (I6G70_10280) - 2138719..2139030 (+) 312 WP_002501910.1 DUF960 family protein -
  I6G70_RS10285 (I6G70_10285) - 2139046..2139342 (+) 297 Protein_1992 DUF1643 domain-containing protein -
  I6G70_RS10290 (I6G70_10290) - 2139563..2140762 (+) 1200 WP_071813246.1 IS110-like element ISSep2 family transposase -
  I6G70_RS10295 (I6G70_10295) - 2140867..2141109 (+) 243 Protein_1994 DUF1643 domain-containing protein -
  I6G70_RS10300 (I6G70_10300) - 2141124..2141344 (+) 221 Protein_1995 hypothetical protein -
  I6G70_RS10305 (I6G70_10305) - 2141507..2141917 (+) 411 WP_001631031.1 DUF2871 domain-containing protein -
  I6G70_RS10315 (I6G70_10315) - 2142589..2143086 (+) 498 WP_001631030.1 GNAT family N-acetyltransferase -
  I6G70_RS10320 (I6G70_10320) - 2143145..2143405 (+) 261 Protein_1998 IS5/IS1182 family transposase -
  I6G70_RS10325 (I6G70_10325) - 2143409..2144611 (-) 1203 WP_001631029.1 restriction endonuclease subunit S -
  I6G70_RS10330 (I6G70_10330) - 2144604..2144747 (-) 144 WP_001631028.1 restriction endonuclease subunit R -
  I6G70_RS10335 (I6G70_10335) - 2144932..2145732 (-) 801 WP_000749912.1 abortive infection family protein -
  I6G70_RS10340 (I6G70_10340) - 2145762..2146916 (-) 1155 WP_011082538.1 ATP-binding protein -
  I6G70_RS10345 (I6G70_10345) - 2147371..2148417 (+) 1047 WP_001042023.1 hypothetical protein -
  I6G70_RS10350 (I6G70_10350) ssb 2148610..2148906 (+) 297 WP_011082537.1 cassette chromosome ssDNA-binding protein -
  I6G70_RS10355 (I6G70_10355) cch1 2148906..2150699 (+) 1794 WP_011082536.1 cassette chromosome replicative helicase -
  I6G70_RS10360 (I6G70_10360) ccrA 2150933..2152282 (+) 1350 WP_011082535.1 cassette chromosome recombinase CcrA Machinery gene
  I6G70_RS10365 (I6G70_10365) ccrB 2152304..2153932 (+) 1629 WP_011082534.1 cassette chromosome recombinase CcrB Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62726.19 Da        Isoelectric Point: 9.9816

>NTDB_id=512740 I6G70_RS10365 WP_011082534.1 2152304..2153932(+) (ccrB) [Staphylococcus epidermidis strain FDAARGOS_913]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKFMNRPELQRMLKDAKEGNIDCVM
IYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWNKVQIRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVARVNQENQVDCASLHHDIAYKQQQYD
EVRIKLNNLIKTIEDNPDLTSVIRPSIQKYDKQLNDIMSQINQLKKQQNEDKPSYNAKKIGKILRYVFHNIEKMKKSQLK
ALYLAVIDRIDIRKDSNHKKQFYVTLKLDNEVIKQVFNDIPLDEVLLSTSSLFLPQPFYLTI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=512740 I6G70_RS10365 WP_011082534.1 2152304..2153932(+) (ccrB) [Staphylococcus epidermidis strain FDAARGOS_913]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTTTCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGATGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAGGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGTAAATTTATGAACAGACCTGAGCTCCAACGTATGTTGAAAGATGCAAAAGAAGGCAATATAGATTGTGTTATG
ATCTACAAAACAAACCGATTAGCTCGTAATACATCGGATCTTCTGAAAATCGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCTTCTGGTAAACTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGGCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTACCACTAGGTTATGACAAAATACCAGATAGTAAACACGAGCTAATGATTAACCAACATGAAGCTAATATTGTAAAATA
TATATTCGAGTCCTATGCCAAAGGACATGGCTATCGTAAAATAGCCAATGCATTGAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGGAAGCATTCCCCCATTAT
TAATCAAGATTTATGGAATAAAGTACAAATACGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACAA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACAACGAATACACTTAAAGAT
GGAACCAAGAAACGTATACGTTACTATTCATGTAGTAATTTTCGCAACAAGGGGTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTCGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTTG
TAGCACGTGTTAATCAAGAAAATCAAGTTGATTGTGCGTCACTTCATCACGATATCGCTTATAAGCAACAACAATATGAT
GAAGTAAGAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGGCCGTCGAT
TCAAAAATATGATAAGCAACTTAATGACATTATGAGTCAAATCAATCAACTCAAAAAACAACAAAATGAAGATAAACCCT
CATATAATGCCAAAAAAATTGGTAAAATATTGCGATACGTCTTTCATAATATTGAGAAAATGAAAAAATCTCAACTTAAA
GCACTGTACTTAGCAGTGATTGATCGCATAGATATTAGAAAAGACAGCAATCACAAAAAACAGTTTTATGTAACACTCAA
ACTTGATAATGAAGTAATTAAACAGGTTTTCAATGATATTCCTCTCGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTT
TACCCCAACCTTTTTATTTAACAATATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(301-356)

Recombinase (Recombinase)

(180-279)

Resolvase, N terminal domain (Resolvase)

(11-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8CQJ7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

92.066

100

0.921