Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Regulator
Locus tag   SIR_RS19790 Genome accession   NC_022246
Coordinates   1993095..1993241 (-) Length   48 a.a.
NCBI ID   WP_003075491.1    Uniprot ID   O33651
Organism   Streptococcus intermedius B196     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1988095..1998241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS19440 (SIR_1896) - 1988104..1990680 (+) 2577 WP_021003375.1 YfhO family protein -
  SIR_RS19455 (SIR_1899) comE 1991004..1991753 (-) 750 WP_003075488.1 competence system response regulator transcription factor ComE Regulator
  SIR_RS19460 (SIR_1900) comD/comD1 1991753..1993078 (-) 1326 WP_003075490.1 GHKL domain-containing protein Regulator
  SIR_RS19790 (SIR_1901) comC 1993095..1993241 (-) 147 WP_003075491.1 bacteriocin Regulator
  SIR_RS19475 (SIR_1903) rlmH 1993518..1993997 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SIR_RS19480 (SIR_1904) htrA 1994201..1995391 (+) 1191 WP_020999302.1 S1C family serine protease Regulator
  SIR_RS19485 (SIR_1905) spo0J 1995446..1996213 (+) 768 WP_021003376.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 48 a.a.        Molecular weight: 5605.69 Da        Isoelectric Point: 10.5532

>NTDB_id=51174 SIR_RS19790 WP_003075491.1 1993095..1993241(-) (comC) [Streptococcus intermedius B196]
MKKLFAKKEVVKKEVVKFKELNDEQLDKVIGGDSRIRMGFDFSKLFGK

Nucleotide


Download         Length: 147 bp        

>NTDB_id=51174 SIR_RS19790 WP_003075491.1 1993095..1993241(-) (comC) [Streptococcus intermedius B196]
ATGAAAAAGTTGTTTGCTAAAAAAGAGGTAGTAAAAAAGGAAGTTGTGAAATTTAAAGAGTTAAATGATGAACAGTTAGA
TAAAGTTATTGGTGGGGATAGTCGAATCAGAATGGGATTTGATTTTTCTAAACTTTTTGGTAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O33651

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Streptococcus sinensis strain Forsyth1A

54.054

77.083

0.417