Detailed information NTG0511570

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: IQE12_RS13870
• Genome accession: NZ_CP065515
• Coordinates: 2789131..2790018 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain GDY8P96A
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2784131..2795018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IQE12_RS13840 (IQE12_13840)	-	2784150..2784242 (+)	93	WP_010956583.1	hypothetical protein	-
IQE12_RS13845 (IQE12_13845)	-	2784350..2784847 (-)	498	WP_001065268.1	glutathione peroxidase	-
IQE12_RS13850 (IQE12_13850)	-	2784857..2785117 (-)	261	WP_001791974.1	hypothetical protein	-
IQE12_RS13855 (IQE12_13855)	-	2785499..2785612 (-)	114	Protein_2713	hypothetical protein	-
IQE12_RS13860 (IQE12_13860)	-	2786271..2788271 (-)	2001	WP_000776740.1	ABC transporter permease	-
IQE12_RS13865 (IQE12_13865)	-	2788268..2789023 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
IQE12_RS13870 (IQE12_13870)	braS	2789131..2790018 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
IQE12_RS13875 (IQE12_13875)	braR	2790029..2790694 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
IQE12_RS13880 (IQE12_13880)	-	2790720..2790920 (-)	201	WP_000604727.1	hypothetical protein	-
IQE12_RS13885 (IQE12_13885)	-	2791118..2792542 (+)	1425	WP_181187883.1	alkaline phosphatase	-
IQE12_RS14480	-	2792602..2792703 (-)	102	WP_000731972.1	SE2200 family small protein	-
IQE12_RS13895 (IQE12_13895)	-	2792825..2793280 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
IQE12_RS13900 (IQE12_13900)	-	2793525..2794286 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=511570 IQE12_RS13870 WP_000143417.1 2789131..2790018(-) (braS) [Staphylococcus aureus strain GDY8P96A]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=511570 IQE12_RS13870 WP_000143417.1 2789131..2790018(-) (braS) [Staphylococcus aureus strain GDY8P96A]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99