Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   IQE12_RS00490 Genome accession   NZ_CP065515
Coordinates   98286..99635 (-) Length   449 a.a.
NCBI ID   WP_181187901.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GDY8P96A     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 93286..104635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IQE12_RS14425 - 93440..93787 (+) 348 Protein_87 HTH domain-containing protein -
  IQE12_RS00455 (IQE12_00455) - 93889..94110 (+) 222 WP_181187895.1 IS3 family transposase -
  IQE12_RS00460 (IQE12_00460) - 94094..94324 (+) 231 WP_181187896.1 hypothetical protein -
  IQE12_RS00465 (IQE12_00465) - 94674..94881 (-) 208 Protein_90 hypothetical protein -
  IQE12_RS00470 (IQE12_00470) - 94883..95404 (-) 522 WP_197668988.1 DUF1643 domain-containing protein -
  IQE12_RS00475 (IQE12_00475) - 95424..95732 (-) 309 WP_181187898.1 DUF960 family protein -
  IQE12_RS00480 (IQE12_00480) - 95817..96167 (-) 351 WP_181187899.1 SAUGI family uracil-DNA glycosylase inhibitor -
  IQE12_RS00485 (IQE12_00485) ccrB 96636..98264 (-) 1629 WP_181187900.1 cassette chromosome recombinase CcrB Machinery gene
  IQE12_RS00490 (IQE12_00490) ccrA 98286..99635 (-) 1350 WP_181187901.1 cassette chromosome recombinase CcrA Machinery gene
  IQE12_RS00495 (IQE12_00495) cch1 99814..101607 (-) 1794 WP_181187902.1 cassette chromosome replicative helicase -
  IQE12_RS00500 (IQE12_00500) ssb 101607..101897 (-) 291 WP_181187903.1 cassette chromosome ssDNA-binding protein -
  IQE12_RS00505 (IQE12_00505) - 102348..103262 (-) 915 WP_197668989.1 hypothetical protein -
  IQE12_RS00510 (IQE12_00510) - 103450..103986 (+) 537 WP_096554311.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52288.17 Da        Isoelectric Point: 9.9488

>NTDB_id=511532 IQE12_RS00490 WP_181187901.1 98286..99635(-) (ccrA) [Staphylococcus aureus strain GDY8P96A]
MKQAIGYLRQSTLKQQSLTAQKQTIQTLAKKHNIQHITFYSDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKSFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLENDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIISATI
YEHAQTIRNKKQLHCIPSENQLKQKIKCPCCGSTLTNMTIRKTNHSLRYYVCPKNMNASRFICDFKGINAENLEKQVLES
CQKFFRDQQLYSKIKHAIENQLKKQRMHDTSNTLTHEKLIEKLAQGTIDVETFREQSQSINLQNKPIQPISDIQIKASLQ
KVIQKSFTLNMLYPYIDVIHITKNKELSGIYLKDEPLNIVNQAVQSSTA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=511532 IQE12_RS00490 WP_181187901.1 98286..99635(-) (ccrA) [Staphylococcus aureus strain GDY8P96A]
ATGAAACAAGCAATCGGTTACTTACGTCAAAGTACACTCAAACAACAATCACTCACTGCACAGAAACAAACTATCCAAAC
ACTCGCGAAAAAACACAATATCCAACACATCACCTTTTATAGTGATAAGCAATCAGGAAGAACTGATAATCGAACAGGGT
ATCAACAAGTCACCGAACGCATTCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGATTACATCGTAAT
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAGTACCATGTTCATATTCTAAGTGTACATGATGGTTATTTTGA
TATGGATAAATCTTTTGATCGTCTAAAACTCAATATTTTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAAACGATAATAAACTTATTACTCGCAAGCCTTATCAGGTACGAAATATTATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAATAATATGGTTCCACCTATTATTTCGGCAACGATA
TATGAACATGCTCAAACAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAAATAAA
ATGTCCTTGTTGTGGTTCAACCCTTACCAATATGACCATTAGAAAAACCAATCATTCATTACGTTATTATGTCTGTCCTA
AAAACATGAATGCATCACGTTTCATATGTGACTTTAAAGGCATAAACGCTGAAAACCTAGAAAAACAGGTCTTAGAATCT
TGCCAAAAATTCTTTCGAGACCAACAGCTCTATTCGAAAATCAAACATGCTATTGAGAATCAACTCAAAAAACAAAGGAT
GCATGATACTAGTAACACATTAACTCATGAAAAGCTCATTGAAAAATTAGCACAAGGAACAATTGATGTAGAAACATTCA
GAGAACAATCTCAATCAATAAACCTACAGAATAAGCCTATACAACCAATAAGTGATATTCAGATAAAAGCATCTCTACAA
AAGGTTATACAAAAAAGTTTCACGTTAAACATGTTATATCCCTATATTGATGTCATTCATATTACTAAAAATAAAGAACT
AAGCGGCATCTATTTAAAAGATGAGCCACTAAACATTGTTAATCAAGCGGTACAATCATCAACTGCCTAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(168-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

76.734

99.555

0.764
  ccrA Staphylococcus aureus N315

71.715

100

0.717