Detailed information NTG0051124

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SPAF_RS03205
• Genome accession: NC_017905
• Coordinates: 612958..615216 (-)
• Length: 752 a.a.
• NCBI ID: WP_041826247.1
• Uniprot ID: -
• Organism: Streptococcus parasanguinis FW213
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 607958..620216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAF_RS03190 (Spaf_0592)	ileS	608828..611620 (+)	2793	WP_003017960.1	isoleucine--tRNA ligase	-
SPAF_RS03195 (Spaf_0593)	-	611874..612176 (-)	303	WP_003012157.1	DUF1827 family protein	-
SPAF_RS03200 (Spaf_0594)	-	612244..612693 (-)	450	WP_014712982.1	NUDIX hydrolase	-
SPAF_RS03205 (Spaf_0595)	clpE	612958..615216 (-)	2259	WP_041826247.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SPAF_RS03210 (Spaf_0597)	-	615464..615694 (+)	231	WP_003005989.1	DUF1797 family protein	-
SPAF_RS03215 (Spaf_0598)	-	615860..616714 (+)	855	WP_041826248.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SPAF_RS03220 (Spaf_0599)	-	616728..617501 (+)	774	WP_041826249.1	HAD hydrolase family protein	-
SPAF_RS03225 (Spaf_0600)	-	617554..618396 (+)	843	WP_041826250.1	NAD(P)H-hydrate dehydratase	-
SPAF_RS03230 (Spaf_0601)	-	618447..619442 (+)	996	WP_014712987.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 83740.97 Da
• Isoelectric Point: 5.2208

>NTDB_id=51124 SPAF_RS03205 WP_041826247.1 612958..615216(-) (clpE) [Streptococcus parasanguinis FW213]
MLCQNCKINESTIHLYTNVNGRQQQVDLCQNCYKIMKTDPNNSFLKGMTQRSQLTGDPFEDFFNNLGNFQSPQEPQTPPT
QSGGSYGGGGYGQNNNRGGGQDPRQARPQKPKGLLEEFGINVTEIARKGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRQREDVILFIDEIHEIVGAG
SAGEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYTD
GAIEAAAILSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYK
EMQGQHVTDQETPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLVLL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGCTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEFMN
RFDGIIEFQPLSKEKLLQIVTLMLDEVNQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLE
HPSEKQLKAVMTSNGNISIKAVHKTAEKKSEA

Nucleotide

• Length: 2259 bp

>NTDB_id=51124 SPAF_RS03205 WP_041826247.1 612958..615216(-) (clpE) [Streptococcus parasanguinis FW213]
ATGCTTTGTCAAAATTGTAAAATAAATGAATCAACCATCCATTTATATACAAATGTAAATGGACGTCAGCAGCAAGTAGA
CCTCTGTCAAAATTGCTATAAAATTATGAAAACAGACCCAAATAACAGCTTCTTGAAAGGCATGACCCAACGGAGCCAAC
TCACTGGAGATCCTTTTGAAGATTTCTTCAATAACCTTGGAAACTTCCAAAGTCCGCAAGAACCTCAAACCCCTCCAACT
CAATCCGGAGGCAGTTATGGAGGTGGCGGCTACGGCCAAAACAATAACCGTGGTGGTGGTCAAGACCCTCGTCAAGCACG
CCCTCAAAAGCCAAAAGGGCTGTTAGAAGAGTTCGGCATCAATGTCACAGAGATTGCCCGCAAAGGAGATATTGACCCTG
TCATTGGCCGTGACGAGGAGATTATCCGTGTCATCGAAATTCTCAACCGTCGAACCAAGAACAACCCGGTTCTGATTGGA
GAGCCTGGGGTCGGAAAAACTGCCGTTGTGGAAGGCCTGGCTCAAAAAATCGTCGATGGCGACGTTCCACATAAATTGCA
AGGAAAAGAAGTCATCCGCCTAGATGTCGTCAGCCTCGTTCAGGGCACAGGCATTCGTGGTCAATTCGAAGAACGCATGC
AAAAATTAATGGATGAAATTCGTCAACGCGAAGATGTTATTCTGTTCATCGACGAAATCCATGAAATTGTTGGTGCAGGA
TCAGCTGGCGAAGGCAATATGGACGCTGGAAATATCCTCAAACCAGCCTTAGCGCGCGGTGAACTCCAATTAGTCGGTGC
TACTACCCTCAATGAATACCGTATCATTGAAAAAGATGCGGCCTTGGAACGTCGGATGCAGCCCGTTAAGGTCGATGAAC
CAACGGTTGAAGAAACCATCACCATCCTCAAGGGTATCCAGAAAAAATACGAAGACTACCACCACGTCCACTATACAGAC
GGAGCTATCGAAGCAGCAGCTATTCTTTCAAACCGCTACATCCAAGATCGCTTCCTGCCAGACAAGGCCATTGATTTGTT
GGATGAAGCCGGTTCTAAAATGAACCTGACTCTGAACTTTGTGGATCCAAAAGTGATTGATCAGCGCTTGATTGAAGCTG
AAAACCTCAAAGCTCAAGCGACGCGCGAAGAAGACTTTGAAAAAGCAGCCTACTTCCGTGACCAAATCGCGAAATACAAG
GAAATGCAAGGTCAACATGTCACTGATCAGGAGACCCCTGTCATCAGTGAAAAAACGATTGAACACATCGTTGAACAAAA
GACTAATATTCCTGTTGGCGATTTGAAAGAAAAAGAACAGTCTCAATTGATCAATCTGGCTTCTGATTTGAAAGCTCATG
TGATCGGTCAAGATGATGCAGTAGATAAAATTGCAAAAGCCATTCGACGCAATCGTGTCGGCCTAGGATCGCCTAACCGT
CCGATCGGAAGCTTCCTCTTTGTCGGACCAACCGGTGTCGGGAAGACCGAACTGTCTAAACAATTGGCGATCGAGCTCTT
TGGCTCTGCAGATAATATGATCCGCTTTGATATGAGCGAATACATGGAAAAACATAGCGTAGCGAAACTAGTCGGAGCTC
CTCCGGGCTATGTTGGCTATGATGAAGCTGGACAACTAACTGAAAAAGTCCGTCGCAATCCTTACTCCCTCGTGTTGTTG
GATGAAGTGGAAAAAGCCCATCCAGACGTCATGCACATGTTCTTGCAAGTCTTGGATGATGGCCGTTTGACAGATGGTCA
AGGCTGTACCGTCAGCTTTAAAGATACCATTATCATCATGACCTCTAATGCTGGAACCGGCAAGGCTGAGGCCAATGTTG
GTTTTGGAGCTGCTCGCGAAGGTCGAACCAACTCTGTACTTGGGGAACTCGGTAACTTCTTTAGCCCTGAATTCATGAAC
CGTTTTGATGGCATCATTGAATTCCAACCTCTATCAAAAGAAAAGCTTCTTCAAATCGTTACCCTCATGCTGGATGAAGT
CAATCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTCAAAGAAAAGTTGGTCGATCTAGGATACG
ATCCAAAAATGGGGGCCCGCCCACTCCGTCGTACCATCCAAGACCATATCGAAGATGCCATTACCGATTATTACTTGGAA
CATCCAAGTGAGAAACAACTCAAAGCAGTCATGACCAGCAATGGGAATATTAGCATCAAAGCTGTTCACAAAACGGCCGA
AAAGAAGTCAGAAGCATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• AAA lid domain (AAA_lid_9) (295-392)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.835	100	0.868
clpE	Streptococcus pneumoniae D39	86.835	100	0.868
clpE	Streptococcus pneumoniae R6	86.835	100	0.868
clpE	Streptococcus pneumoniae TIGR4	86.835	100	0.868
clpE	Streptococcus mutans UA159	83.712	99.601	0.834
clpC	Lactococcus lactis subsp. cremoris KW2	75.297	100	0.758
clpC	Bacillus subtilis subsp. subtilis str. 168	50.283	93.883	0.472
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.546	86.702	0.412
clpC	Streptococcus pneumoniae Rx1	47.68	83.112	0.396
clpC	Streptococcus pneumoniae D39	47.68	83.112	0.396
clpC	Streptococcus pneumoniae TIGR4	47.52	83.112	0.395
clpC	Streptococcus thermophilus LMD-9	46.87	82.846	0.388
clpC	Streptococcus mutans UA159	46.72	83.112	0.388
clpC	Streptococcus thermophilus LMG 18311	46.624	82.713	0.386