Detailed information NTG0051122

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SPAF_RS03055
• Genome accession: NC_017905
• Coordinates: 583778..584860 (+)
• Length: 360 a.a.
• NCBI ID: WP_014712969.1
• Uniprot ID: I1ZKK2
• Organism: Streptococcus parasanguinis FW213
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 578778..589860

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPAF_RS03025 (Spaf_0561)	-	578917..579288 (-)	372	WP_013903193.1	hypothetical protein	-
SPAF_RS03030 (Spaf_0562)	-	579285..580697 (-)	1413	WP_014712964.1	Y-family DNA polymerase	-
SPAF_RS03035 (Spaf_0563)	-	580700..581377 (-)	678	WP_041826243.1	XRE family transcriptional regulator	-
SPAF_RS03040 (Spaf_0564)	asnA	581537..582529 (+)	993	WP_003005888.1	aspartate--ammonia ligase	-
SPAF_RS03045 (Spaf_0565)	rsmD	582777..583316 (+)	540	WP_041818095.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SPAF_RS03050 (Spaf_0566)	coaD	583306..583794 (+)	489	WP_014712968.1	pantetheine-phosphate adenylyltransferase	-
SPAF_RS03055 (Spaf_0567)	sepM	583778..584860 (+)	1083	WP_014712969.1	SepM family pheromone-processing serine protease	Regulator
SPAF_RS03060 (Spaf_0568)	ccdA2	585023..585733 (+)	711	WP_013903200.1	thiol-disulfide oxidoreductase-associated membrane protein CcdA2	-
SPAF_RS03065 (Spaf_0569)	-	585760..586083 (+)	324	WP_014712970.1	hypothetical protein	-
SPAF_RS03070 (Spaf_0570)	-	586140..586700 (+)	561	WP_041826525.1	redoxin family protein	-
SPAF_RS03075 (Spaf_0571)	msrB	586712..587833 (+)	1122	WP_014712972.1	peptide-methionine (R)-S-oxide reductase MsrB	-
SPAF_RS03080 (Spaf_0572)	-	587892..588626 (+)	735	WP_041826244.1	response regulator	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 39077.75 Da
• Isoelectric Point: 9.2944

>NTDB_id=51122 SPAF_RS03055 WP_014712969.1 583778..584860(+) (sepM) [Streptococcus parasanguinis FW213]
MTQANKPSLPTKKKKGRLKEYRWPIAGVLFLLLLLAAFVIRLPYYIEMPGTAEDIRSVMTVDGKMDTKSGSYDFVTVAVK
EATPADLIYAWATPFTDIYSAKDMTGGSSSQEFTRINQFYMETSQNMAIYQGLKTAGKETQMDFLGVYVMQVADDSTFKG
ILNIADTVTGVNGKTFKSSTELIDYVGSQKIGDPVSVTYIEDGQTKTADGKIIKLSNGKNGIGISLIDRTEAKGDVPVQF
ATQGIGGPSAGMMFSLAIYTQVADPDLRQGRHIAGTGTINQDGTVGDIGGIDKKVVAADKEGAEIFFAPNNPVSKEEKKA
NPKAKSNYETAKEAAKQIHSKMKIVPVKTLQDAIDYLKKK

Nucleotide

• Length: 1083 bp

>NTDB_id=51122 SPAF_RS03055 WP_014712969.1 583778..584860(+) (sepM) [Streptococcus parasanguinis FW213]
ATGACACAAGCGAATAAACCAAGCTTGCCTACAAAAAAGAAAAAAGGACGATTGAAAGAATACCGATGGCCGATTGCAGG
CGTTCTTTTCTTGCTCCTCTTGCTAGCTGCTTTTGTGATTCGCCTTCCCTATTATATTGAAATGCCGGGTACAGCAGAAG
ATATTCGATCGGTCATGACAGTGGATGGAAAAATGGATACCAAGTCAGGATCTTATGACTTTGTAACCGTAGCAGTGAAA
GAAGCGACTCCGGCTGATTTGATCTATGCTTGGGCGACACCTTTTACAGATATCTACTCTGCCAAGGATATGACAGGCGG
TAGTTCGAGCCAAGAATTTACGCGGATTAACCAATTCTATATGGAAACCTCGCAAAATATGGCCATCTACCAAGGGTTAA
AGACAGCTGGAAAAGAAACCCAGATGGACTTTCTTGGTGTTTATGTCATGCAAGTGGCAGATGACTCGACCTTTAAGGGA
ATCTTGAACATTGCGGATACCGTCACCGGTGTGAATGGCAAGACCTTTAAGAGTTCCACAGAATTGATTGACTATGTTGG
TTCTCAAAAAATTGGCGACCCCGTTTCGGTGACCTATATTGAGGATGGACAAACCAAGACAGCAGATGGAAAGATCATCA
AATTGTCCAACGGGAAAAACGGAATCGGGATTAGCTTGATCGACCGGACTGAAGCCAAAGGCGATGTTCCTGTCCAATTT
GCGACTCAAGGGATTGGTGGCCCAAGTGCCGGCATGATGTTTAGCCTAGCCATCTACACTCAAGTAGCTGATCCAGATCT
TCGTCAGGGACGCCATATTGCAGGGACAGGAACCATTAACCAAGATGGGACGGTTGGCGATATCGGTGGGATTGACAAGA
AAGTCGTCGCAGCCGATAAAGAAGGAGCAGAAATTTTCTTTGCCCCTAATAATCCAGTTTCCAAAGAAGAAAAGAAAGCC
AATCCCAAGGCCAAATCAAACTATGAAACCGCTAAAGAAGCAGCGAAACAAATTCATTCGAAGATGAAAATCGTTCCCGT
CAAAACACTTCAAGACGCCATTGATTATTTGAAGAAGAAGTAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (246-352)

• PDZ domain (PDZ_2) (145-209)

3D structure

• AlphaFold DB: I1ZKK2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.411	94.722	0.572