Detailed information NTG0511191

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STT128_RS03355
• Genome accession: NZ_CP065500
• Coordinates: 630621..631622 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain ST128
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 625621..636622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS03335 (STT128_03395)	smpB	626728..627192 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STT128_RS03340 (STT128_03400)	-	627346..628752 (+)	1407	WP_082308872.1	Cof-type HAD-IIB family hydrolase	-
STT128_RS03345 (STT128_03405)	-	628754..629119 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
STT128_RS03350 (STT128_03410)	-	629222..630307 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
STT128_RS03355 (STT128_03415)	ccpA	630621..631622 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STT128_RS03360 (STT128_03420)	-	631681..631878 (+)	198	WP_014608125.1	hypothetical protein	-
STT128_RS03365	-	631984..632208 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
STT128_RS03370 (STT128_03425)	-	632209..632748 (+)	540	WP_011680936.1	hypothetical protein	-
STT128_RS03375 (STT128_03430)	-	632761..633876 (+)	1116	WP_011680937.1	glycerate kinase	-
STT128_RS03380 (STT128_03435)	-	633923..634378 (-)	456	WP_011680938.1	YueI family protein	-
STT128_RS03385 (STT128_03440)	eno	634587..635891 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
STT128_RS03390 (STT128_03445)	-	636043..636227 (-)	185	Protein_606	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=511191 STT128_RS03355 WP_004197422.1 630621..631622(+) (ccpA) [Streptococcus thermophilus strain ST128]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=511191 STT128_RS03355 WP_004197422.1 630621..631622(+) (ccpA) [Streptococcus thermophilus strain ST128]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547