Detailed information NTG0511161

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STAVA116_RS08250
• Genome accession: NZ_CP065498
• Coordinates: 1598876..1599313 (-)
• Length: 145 a.a.
• NCBI ID: WP_022096897.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain AVA116
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1593876..1604313

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STAVA116_RS08215 (STAVA116_08165)	-	1593930..1594592 (-)	663	WP_087010194.1	type II CAAX endopeptidase family protein	-
STAVA116_RS08220 (STAVA116_08170)	-	1594695..1595138 (-)	444	WP_087010195.1	CAAX protease	-
STAVA116_RS08225	-	1595212..1595637 (-)	426	WP_087010196.1	CPBP family intramembrane glutamic endopeptidase	-
STAVA116_RS08230 (STAVA116_08180)	-	1595885..1596082 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
STAVA116_RS08235 (STAVA116_08185)	-	1596331..1597524 (-)	1194	WP_087010197.1	acetate kinase	-
STAVA116_RS08240 (STAVA116_08190)	comYH	1597580..1598536 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STAVA116_RS08245 (STAVA116_08195)	comGG	1598581..1598898 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STAVA116_RS08250 (STAVA116_08200)	comYF	1598876..1599313 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
STAVA116_RS08255 (STAVA116_08205)	comGE	1599297..1599590 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STAVA116_RS08260 (STAVA116_08210)	comYD	1599562..1599990 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STAVA116_RS08265 (STAVA116_08215)	comYC	1599950..1600276 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STAVA116_RS08270 (STAVA116_08220)	comYB	1600273..1601373 (-)	1101	WP_157659050.1	competence type IV pilus assembly protein ComGB	Machinery gene
STAVA116_RS08275 (STAVA116_08225)	comGA/cglA/cilD	1601255..1602196 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STAVA116_RS08280 (STAVA116_08230)	-	1602277..1602639 (-)	363	WP_087010198.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.89 Da
• Isoelectric Point: 8.9784

>NTDB_id=511161 STAVA116_RS08250 WP_022096897.1 1598876..1599313(-) (comYF) [Streptococcus thermophilus strain AVA116]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=511161 STAVA116_RS08250 WP_022096897.1 1598876..1599313(-) (comYF) [Streptococcus thermophilus strain AVA116]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441