Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STAVA116_RS01595 Genome accession   NZ_CP065498
Coordinates   294734..296251 (+) Length   505 a.a.
NCBI ID   WP_002949640.1    Uniprot ID   A0A060BQ50
Organism   Streptococcus thermophilus strain AVA116     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 289734..301251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA116_RS01565 - 290014..290184 (+) 171 Protein_268 ascorbate 6-phosphate lactonase -
  STAVA116_RS01570 (STAVA116_01570) - 290201..290872 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  STAVA116_RS01575 (STAVA116_01575) - 290912..292276 (-) 1365 WP_082302294.1 potassium transporter TrkG -
  STAVA116_RS01580 (STAVA116_01580) rsmG 292346..293059 (-) 714 WP_002949634.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STAVA116_RS01585 (STAVA116_01585) - 293356..293892 (+) 537 WP_002949636.1 YceD family protein -
  STAVA116_RS01590 (STAVA116_01590) covR 294048..294737 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  STAVA116_RS01595 (STAVA116_01595) covS 294734..296251 (+) 1518 WP_002949640.1 HAMP domain-containing histidine kinase Regulator
  STAVA116_RS01600 (STAVA116_01600) nrdR 296373..296852 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STAVA116_RS01605 (STAVA116_01605) - 296849..298024 (+) 1176 WP_002949643.1 DnaD domain protein -
  STAVA116_RS01610 (STAVA116_01610) dnaI 298028..298930 (+) 903 WP_002946786.1 primosomal protein DnaI -
  STAVA116_RS01615 (STAVA116_01615) der 299036..300346 (+) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57536.93 Da        Isoelectric Point: 5.2689

>NTDB_id=511121 STAVA116_RS01595 WP_002949640.1 294734..296251(+) (covS) [Streptococcus thermophilus strain AVA116]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=511121 STAVA116_RS01595 WP_002949640.1 294734..296251(+) (covS) [Streptococcus thermophilus strain AVA116]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCATGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BQ50

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.622

99.406

0.941