Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SIR_RS13440 Genome accession   NC_022246
Coordinates   733141..733611 (+) Length   156 a.a.
NCBI ID   WP_021002685.1    Uniprot ID   T1ZDU1
Organism   Streptococcus intermedius B196     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 728141..738611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS13425 (SIR_0722) - 730297..731010 (+) 714 WP_003072599.1 DUF805 domain-containing protein -
  SIR_RS13430 (SIR_0723) - 731450..732436 (+) 987 WP_021002683.1 Gfo/Idh/MocA family protein -
  SIR_RS13435 (SIR_0724) - 732461..733114 (+) 654 WP_021002684.1 uracil-DNA glycosylase -
  SIR_RS13440 (SIR_0725) mutX 733141..733611 (+) 471 WP_021002685.1 NUDIX hydrolase Machinery gene
  SIR_RS13445 (SIR_0726) - 733623..734897 (+) 1275 WP_021002686.1 dihydroorotase -
  SIR_RS13450 (SIR_0727) metK 735163..736353 (+) 1191 WP_021002687.1 methionine adenosyltransferase -
  SIR_RS13455 (SIR_0728) - 736689..737948 (+) 1260 WP_021002688.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SIR_RS13460 (SIR_0729) - 738027..738578 (+) 552 WP_003072608.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 18145.64 Da        Isoelectric Point: 4.4522

>NTDB_id=51096 SIR_RS13440 WP_021002685.1 733141..733611(+) (mutX) [Streptococcus intermedius B196]
MVKLATICYVDNGKEFLMLYRNKKPNDVHAGKWIGVGGKLENGETPQECAVREIFEETGLRVKKPILKGIITFPEFTPNH
DWYTYVFKVTEFEGELIDCDEGTLEWVPYEQVLSKPTWEGDLTFISWILEEKPFFSAKFSYKGETLVESHVDFYED

Nucleotide


Download         Length: 471 bp        

>NTDB_id=51096 SIR_RS13440 WP_021002685.1 733141..733611(+) (mutX) [Streptococcus intermedius B196]
ATGGTTAAATTAGCAACGATTTGCTATGTGGACAATGGAAAAGAATTTCTGATGTTATATCGAAATAAAAAGCCCAATGA
TGTCCATGCTGGCAAGTGGATTGGTGTTGGTGGAAAATTAGAAAATGGCGAAACACCACAGGAGTGTGCTGTCCGAGAAA
TCTTTGAAGAGACAGGATTGCGCGTGAAAAAGCCGATATTAAAAGGTATTATCACTTTTCCAGAGTTTACACCGAACCAT
GACTGGTACACTTATGTATTTAAAGTGACAGAGTTTGAGGGAGAACTGATTGACTGCGATGAAGGTACTTTAGAATGGGT
ACCTTATGAACAAGTTCTATCTAAACCAACTTGGGAGGGAGATCTTACTTTTATATCTTGGATTTTAGAAGAAAAACCGT
TTTTCTCGGCCAAATTTTCTTACAAAGGAGAGACGTTAGTGGAGAGCCATGTTGATTTTTATGAAGATTAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(5-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZDU1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

78.71

99.359

0.782

Multiple sequence alignment