Detailed information NTG0510903

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST4145_RS05335
• Genome accession: NZ_CP065492
• Coordinates: 1029608..1030489 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4145
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1024608..1035489

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4145_RS05310 (ST4145_05260)	vicR	1025315..1026022 (-)	708	WP_024009930.1	response regulator YycF	Regulator
ST4145_RS05315 (ST4145_05265)	-	1026546..1027313 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
ST4145_RS05320 (ST4145_05270)	-	1027325..1028158 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
ST4145_RS05325 (ST4145_05275)	-	1028176..1028874 (+)	699	WP_002953144.1	amino acid ABC transporter permease	-
ST4145_RS05330 (ST4145_05280)	-	1028886..1029536 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
ST4145_RS05335 (ST4145_05285)	endA	1029608..1030489 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4145_RS05340 (ST4145_05290)	-	1030551..1030739 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST4145_RS05345 (ST4145_05295)	murA	1030741..1032012 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4145_RS05350 (ST4145_05300)	-	1032082..1032318 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST4145_RS05355 (ST4145_05305)	galE	1032506..1033519 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
ST4145_RS05360 (ST4145_05310)	-	1033534..1033989 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=510903 ST4145_RS05335 WP_011681210.1 1029608..1030489(-) (endA) [Streptococcus thermophilus strain 4145]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510903 ST4145_RS05335 WP_011681210.1 1029608..1030489(-) (endA) [Streptococcus thermophilus strain 4145]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594