Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   STCNRZ1575_RS01725 Genome accession   NZ_CP065490
Coordinates   310311..311828 (+) Length   505 a.a.
NCBI ID   WP_084828485.1    Uniprot ID   A0A0E2Q5R4
Organism   Streptococcus thermophilus strain CNRZ1575     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 305311..316828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ1575_RS01695 - 305590..305760 (+) 171 Protein_268 ascorbate 6-phosphate lactonase -
  STCNRZ1575_RS01700 (STCNRZ1575_01720) - 305777..306448 (-) 672 WP_064355629.1 TrkA family potassium uptake protein -
  STCNRZ1575_RS01705 (STCNRZ1575_01725) - 306488..307852 (-) 1365 WP_269149496.1 potassium transporter TrkG -
  STCNRZ1575_RS01710 (STCNRZ1575_01730) rsmG 307922..308635 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  STCNRZ1575_RS01715 (STCNRZ1575_01735) - 308932..309468 (+) 537 WP_084825774.1 YceD family protein -
  STCNRZ1575_RS01720 (STCNRZ1575_01740) covR 309625..310314 (+) 690 WP_084828484.1 response regulator transcription factor Regulator
  STCNRZ1575_RS01725 (STCNRZ1575_01745) covS 310311..311828 (+) 1518 WP_084828485.1 HAMP domain-containing histidine kinase Regulator
  STCNRZ1575_RS01730 (STCNRZ1575_01750) nrdR 311951..312430 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  STCNRZ1575_RS01735 (STCNRZ1575_01755) - 312427..313602 (+) 1176 WP_100262514.1 DnaD domain protein -
  STCNRZ1575_RS01740 (STCNRZ1575_01760) dnaI 313606..314508 (+) 903 WP_084828487.1 primosomal protein DnaI -
  STCNRZ1575_RS01745 (STCNRZ1575_01765) der 314614..315924 (+) 1311 WP_260214323.1 ribosome biogenesis GTPase Der -
  STCNRZ1575_RS01750 (STCNRZ1575_01770) - 315988..316656 (+) 669 Protein_279 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57568.03 Da        Isoelectric Point: 5.5179

>NTDB_id=510766 STCNRZ1575_RS01725 WP_084828485.1 310311..311828(+) (covS) [Streptococcus thermophilus strain CNRZ1575]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAAFY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLKFYYALKERLIFLLIFLEVGMTVLVIAVIVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGALALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=510766 STCNRZ1575_RS01725 WP_084828485.1 310311..311828(+) (covS) [Streptococcus thermophilus strain CNRZ1575]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCTTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGAAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAATTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACAATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGCTTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTCCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGGTTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

ArlS sensor domain (ArlS_N)

(39-187)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q5R4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.223

99.406

0.937