Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   SIR_RS11315 Genome accession   NC_022246
Coordinates   304244..307069 (+) Length   941 a.a.
NCBI ID   WP_021002442.1    Uniprot ID   T1ZBS2
Organism   Streptococcus intermedius B196     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 299244..312069
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS11285 (SIR_0304) rpsF 300366..300656 (+) 291 WP_003074536.1 30S ribosomal protein S6 -
  SIR_RS11290 (SIR_0305) ssbA 300668..301138 (+) 471 WP_003074535.1 single-stranded DNA-binding protein Machinery gene
  SIR_RS11295 (SIR_0306) rpsR 301175..301414 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  SIR_RS11300 (SIR_0307) - 301823..302332 (+) 510 WP_021002441.1 GNAT family N-acetyltransferase -
  SIR_RS11305 (SIR_0308) - 302484..303161 (-) 678 WP_003074532.1 DUF1129 domain-containing protein -
  SIR_RS11310 (SIR_0309) - 303177..304121 (-) 945 WP_003070861.1 magnesium transporter CorA family protein -
  SIR_RS11315 (SIR_0310) uvrA 304244..307069 (+) 2826 WP_021002442.1 excinuclease ABC subunit UvrA Machinery gene
  SIR_RS11320 (SIR_0311) - 307107..307862 (-) 756 WP_021002443.1 hypothetical protein -
  SIR_RS11325 (SIR_0312) - 308010..309071 (+) 1062 WP_021002444.1 M24 family metallopeptidase -
  SIR_RS11330 (SIR_0313) efp 309130..309690 (+) 561 WP_003026309.1 elongation factor P -
  SIR_RS11335 (SIR_0314) - 309800..310189 (+) 390 WP_003074522.1 Asp23/Gls24 family envelope stress response protein -
  SIR_RS11340 (SIR_0315) nusB 310182..310607 (+) 426 WP_041787361.1 transcription antitermination factor NusB -
  SIR_RS11345 (SIR_0316) comR/comR2 310639..311121 (+) 483 WP_021002446.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 941 a.a.        Molecular weight: 103930.42 Da        Isoelectric Point: 6.8105

>NTDB_id=51076 SIR_RS11315 WP_021002442.1 304244..307069(+) (uvrA) [Streptococcus intermedius B196]
MQDKIIIHGARAHNLKNIDVTIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVNQVLELPERQRLQILAPIIRKKK
GQHKTIFDKIQKDGYVRVRVDGDIYDVTEVPELSKTKKHDIEVVVDRIVIKKSVRSRLFDSIEAALRLAEGYVVIDTMDG
KELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSDCDGLGIKLEVDLDLVVPDSSKTLREGALAPWNPISSSYYPQML
AQAMEAFGIEMDKPFEELSEEEKRLIFFGSDGREFHFHYENEFGGVRDIDIPFEGVVTNINRRYHETNSDFTRSQMRLYM
NELTCASCHGYRLNPQALSVKVGGEGGLNIGQVSDLSIADHLELLSHLTLTENEVAIATPIIKEIRDRLTFLHNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNNRLIASLKKMRDLGNTLIVVEHDEDTMREADWLI
DVGPGAGVFGGEIVAAGTPEQVAKSKKSITGQYLSGKREIPVPLERRVGNGRFIEVTGAREHNLQNITARFPLGKFIAVT
GVSGSGKSTLVNSILKKAIAQKLNRNSDKPGKFKNISGIEHIDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAKTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVHYKEKNIAQVLDMTVNDAVEFF
KHIPKIERKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIAKLLQVLSRFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGIGGGTIIATGTPEEVAANSASYTGQYLKGKLK

Nucleotide


Download         Length: 2826 bp        

>NTDB_id=51076 SIR_RS11315 WP_021002442.1 304244..307069(+) (uvrA) [Streptococcus intermedius B196]
ATGCAGGATAAAATTATCATTCATGGAGCGCGAGCCCATAATTTAAAAAATATTGATGTTACGATTCCGCGGGACAAGTT
GGTTGTAGTGACAGGGCTGTCTGGTTCAGGCAAGTCTAGCTTAGCTTTTGATACTCTCTATGCAGAGGGACAACGGCGTT
ATGTAGAAAGCCTGTCGGCTTATGCCCGTCAATTTTTGGGTAACATGGAAAAACCAGATGTGGATTCAATTGACGGTCTT
AGCCCTGCTATTTCCATTGACCAAAAAACGACTAGCAAGAATCCTCGTTCAACAGTCGGAACAGTTACAGAAATCAATGA
TTATCTCCGTTTGCTCTATGCGCGTGTGGGAACTCCATATTGTATCAATGGGCATGGAGCCATTAAAGCTTCTTCTGTAG
AACAAATCGTCAATCAAGTTTTGGAATTACCCGAACGTCAGAGATTACAAATTCTAGCGCCAATTATCCGTAAGAAAAAA
GGACAGCACAAGACAATCTTTGATAAAATTCAAAAAGATGGATATGTTCGGGTGCGCGTGGATGGAGATATTTATGATGT
TACCGAAGTCCCAGAGCTTTCTAAAACGAAAAAGCACGATATCGAAGTAGTGGTGGATCGGATTGTCATTAAGAAGAGTG
TACGCAGTCGATTATTTGATTCGATTGAAGCAGCTTTAAGACTTGCGGAAGGCTACGTGGTGATTGATACGATGGATGGC
AAAGAATTACTCTTTTCCGAGCATTATGCGTGTCCAGTCTGTGGTTTTACGGTTCCTGAACTCGAACCGCGCCTTTTCTC
TTTTAATGCCCCATTTGGATCCTGCTCTGACTGTGACGGCTTAGGTATCAAGTTAGAGGTTGATTTGGATCTTGTAGTGC
CTGATAGTAGTAAAACATTACGTGAAGGAGCTCTAGCACCGTGGAATCCAATTTCTTCTAGTTATTATCCGCAAATGTTA
GCTCAGGCGATGGAAGCCTTTGGCATCGAGATGGATAAGCCTTTTGAGGAATTGAGTGAGGAAGAAAAACGGCTGATTTT
CTTTGGCTCAGATGGTCGGGAGTTCCATTTTCACTATGAAAATGAATTTGGTGGCGTGCGGGATATCGACATCCCTTTTG
AAGGAGTAGTAACCAATATCAACCGCCGCTATCATGAAACTAACAGTGATTTTACCCGTAGCCAAATGCGTCTTTATATG
AATGAGTTGACTTGTGCAAGTTGCCATGGTTATCGATTGAATCCACAAGCCTTGTCTGTTAAAGTGGGGGGTGAAGGTGG
TCTTAATATTGGGCAAGTATCTGATTTGTCTATTGCAGATCATTTAGAATTACTTTCTCATCTGACTTTGACTGAAAATG
AAGTGGCCATTGCAACACCGATTATTAAAGAAATTCGCGATCGCTTGACTTTTCTTCATAATGTCGGGCTTAATTATCTA
ACTCTATCTCGTTCTGCGGGAACATTGTCGGGTGGTGAGAGTCAGCGGATTCGCTTGGCAACTCAAATTGGTTCCAATCT
CAGTGGTGTTCTTTATATCTTGGATGAGCCCTCTATTGGTCTACACCAGCGGGATAACAATCGCTTGATTGCCAGTCTCA
AAAAAATGCGTGATTTGGGCAATACTCTCATTGTGGTTGAACATGATGAAGATACTATGCGTGAAGCTGATTGGTTGATT
GATGTTGGACCTGGAGCAGGTGTTTTTGGTGGTGAAATTGTTGCGGCAGGCACTCCAGAGCAAGTTGCAAAAAGCAAGAA
ATCAATTACAGGTCAGTATTTATCGGGCAAACGTGAAATTCCAGTGCCATTGGAGCGCCGCGTAGGAAACGGCCGCTTTA
TTGAAGTAACAGGTGCGCGAGAGCACAATTTGCAAAACATCACGGCCCGCTTCCCGTTAGGAAAATTTATAGCCGTGACG
GGAGTTTCCGGTTCTGGGAAATCGACCTTGGTTAATTCCATTTTGAAAAAAGCAATCGCTCAAAAGCTCAATCGTAATTC
AGACAAACCGGGTAAATTCAAAAATATTTCAGGAATTGAGCATATTGATCGTTTGATTGATATTGACCAGAGCCCGATCG
GCCGAACACCAAGATCCAATCCAGCGACGTATACTGGCGTCTTTGATGATATTCGCGATCTCTTTGCTAAGACTAACGAA
GCTAAGATTCGTGGGTATAAAAAAGGGCGTTTCTCTTTCAATGTGAAGGGGGGACGCTGCGAGGCCTGCTCTGGGGATGG
GATTATCAAGATTGAGATGCACTTTTTACCAGATGTTTATGTCCCTTGTGAGGTTTGCCATGGAACACGGTACAATAGTG
AAACCTTGGAGGTGCACTACAAAGAGAAAAACATTGCTCAAGTTTTGGATATGACGGTCAATGATGCAGTGGAATTTTTT
AAGCATATTCCTAAAATTGAGCGGAAACTTCAGACCATCAAAGACGTAGGACTAGGATATGTAACGTTAGGACAACCTGC
CACAACTCTTTCTGGTGGTGAGGCTCAGCGGATGAAACTAGCCAGCGAACTTCACAAGCGCTCAACAGGTAAGTCTTTCT
ATATTCTGGATGAACCAACTACAGGTCTGCACACGGAGGATATTGCGAAACTTCTCCAAGTGCTATCACGTTTTGTAGAC
GATGGCAACACGGTTCTCGTTATCGAGCATAATCTGGACGTTATTAAGACGGCCGATCACATTATTGATCTTGGACCAGA
AGGTGGTATTGGTGGAGGTACTATTATTGCTACTGGTACACCAGAAGAAGTAGCTGCAAACTCTGCTAGCTATACTGGCC
AGTATCTAAAAGGAAAGTTAAAATAA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-238)

ABC transporter (ABC_tran)

(624-860)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZBS2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

89.894

99.894

0.898
  uvrA Streptococcus pneumoniae TIGR4

89.894

99.894

0.898
  uvrA Streptococcus pneumoniae D39

89.894

99.894

0.898

Multiple sequence alignment