Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   STAVA1121_RS01485 Genome accession   NZ_CP065488
Coordinates   265434..266333 (+) Length   299 a.a.
NCBI ID   WP_347114255.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain AVA1121     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 260434..271333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STAVA1121_RS01465 (STAVA1121_01435) trkA 261573..262922 (-) 1350 WP_011225444.1 Trk system potassium transporter TrkA -
  STAVA1121_RS01470 (STAVA1121_01440) - 263211..263720 (+) 510 WP_011680717.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  STAVA1121_RS01475 (STAVA1121_01445) - 264030..264587 (+) 558 WP_024704183.1 ECF transporter S component -
  STAVA1121_RS01480 (STAVA1121_01450) - 264590..265240 (+) 651 WP_347131365.1 phosphatase PAP2 family protein -
  STAVA1121_RS01485 (STAVA1121_01455) comR 265434..266333 (+) 900 WP_347114255.1 XRE family transcriptional regulator Regulator
  STAVA1121_RS01490 (STAVA1121_01460) - 266571..267749 (+) 1179 Protein_240 ABC transporter transmembrane domain-containing protein -
  STAVA1121_RS01495 comA 267771..267980 (+) 210 WP_002946147.1 hypothetical protein Regulator
  STAVA1121_RS01500 (STAVA1121_01475) - 268035..268603 (+) 569 Protein_242 ATP-binding cassette domain-containing protein -
  STAVA1121_RS01505 - 268834..269022 (+) 189 WP_224103239.1 hypothetical protein -
  STAVA1121_RS01510 - 269030..269275 (-) 246 WP_233014559.1 hypothetical protein -
  STAVA1121_RS01515 - 269244..269591 (-) 348 WP_347131367.1 DUF4153 domain-containing protein -
  STAVA1121_RS01520 - 269516..270412 (-) 897 WP_347131368.1 urease cluster protein -
  STAVA1121_RS01525 (STAVA1121_01490) - 270817..271332 (+) 516 WP_002949547.1 AmiS/UreI family transporter -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35302.78 Da        Isoelectric Point: 5.2252

>NTDB_id=510646 STAVA1121_RS01485 WP_347114255.1 265434..266333(+) (comR) [Streptococcus thermophilus strain AVA1121]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLNRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=510646 STAVA1121_RS01485 WP_347114255.1 265434..266333(+) (comR) [Streptococcus thermophilus strain AVA1121]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAAATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMG 18311

99.666

100

0.997
  comR Streptococcus thermophilus LMD-9

98.997

100

0.99
  comR Streptococcus salivarius strain HSISS4

94.983

100

0.95
  comR Streptococcus salivarius SK126

94.314

100

0.943
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421