Detailed information NTG0510559

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: STR1_RS07825
• Genome accession: NZ_CP065486
• Coordinates: 1526743..1527819 (-)
• Length: 358 a.a.
• NCBI ID: WP_171815041.1
• Uniprot ID: A0A0E2QFS3
• Organism: Streptococcus thermophilus strain R1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1521743..1532819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR1_RS07805 (STR1_07855)	-	1522853..1524919 (-)	2067	WP_095559435.1	sodium:proton antiporter	-
STR1_RS07810 (STR1_07860)	-	1524928..1525170 (-)	243	WP_011226461.1	hypothetical protein	-
STR1_RS07815 (STR1_07865)	-	1525167..1525715 (-)	549	WP_084829063.1	class I SAM-dependent methyltransferase	-
STR1_RS07820 (STR1_07870)	-	1525708..1526658 (-)	951	WP_084829064.1	TIGR01212 family radical SAM protein	-
STR1_RS07825 (STR1_07875)	sepM	1526743..1527819 (-)	1077	WP_171815041.1	SepM family pheromone-processing serine protease	Regulator
STR1_RS07830 (STR1_07880)	coaD	1527797..1528294 (-)	498	WP_095559436.1	pantetheine-phosphate adenylyltransferase	-
STR1_RS07835 (STR1_07885)	rsmD	1528328..1528927 (-)	600	Protein_1502	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
STR1_RS07840 (STR1_07890)	trxB	1529018..1529971 (-)	954	WP_255136104.1	thioredoxin-disulfide reductase	-
STR1_RS07845 (STR1_07895)	-	1530004..1530228 (-)	225	WP_002951743.1	DUF4059 family protein	-
STR1_RS07850 (STR1_07900)	-	1530443..1531186 (-)	744	WP_011681551.1	amino acid ABC transporter ATP-binding protein	-
STR1_RS07855 (STR1_07905)	-	1531186..1531932 (-)	747	WP_095559509.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 39156.06 Da
• Isoelectric Point: 9.6075

>NTDB_id=510559 STR1_RS07825 WP_171815041.1 1526743..1527819(-) (sepM) [Streptococcus thermophilus strain R1]
MANKTKSKSLLEKMWRIKWRLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVNKKADDSKGSYNFVAVAQTKAT
LALMLYAQFNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAVYQGLTLAGKEVSLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSTDMIKYVQGLKLGSKVKVTYMRDGKEKTATGKIIKIANGKNGIGIGLTDHTEIKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGAVGDIGGAYLKVKSAADSGADIFFVPNNLVTKEMKKADPD
AKTNYQEAKEAAEKLGTKMKIVPVKTAQEAIDFLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=510559 STR1_RS07825 WP_171815041.1 1526743..1527819(-) (sepM) [Streptococcus thermophilus strain R1]
GTGGCAAACAAGACAAAATCTAAATCGCTATTAGAGAAAATGTGGCGTATTAAGTGGCGGTTATTAAGTATTTTTACGGT
ACTTTTCCTCCTTTTTGCCCTCTTTTTCCCGCTCAATAATTACTATGTGGAGCTTCCGGGTGGTGCTTTTGATACCAAGG
AAGTCTTGACAGTGAATAAGAAAGCTGATGATTCTAAGGGCTCCTATAATTTTGTGGCGGTGGCTCAAACCAAGGCGACT
TTGGCCTTGATGCTCTATGCTCAGTTTAATGATTTTGCAAAGCTTCAAACGGCTGAAGAGGCAACTGGAAATTACTCTGA
TGAAGATTTCATGCGCATCAACCAATTTTACATGGAGACTTCTCAAAACCAAGCGGTTTATCAGGGCTTGACTCTGGCTG
GTAAGGAGGTTAGTTTGGAGTATATGGGTGTCTATGTGCTTCAGGTTGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCTGATACGGTGACGGCTGTTAATGGTAAGACCTTTGATAATTCTACTGACATGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAGGTCAAGGTCACTTATATGAGAGATGGCAAAGAAAAGACTGCTACTGGTAAGATTATTAAGATTGCCA
ATGGCAAAAATGGTATTGGTATCGGCCTAACGGACCATACTGAGATCAAGAGTCCTGAGAATGTTAAGTTTAAACTGGAT
GGTGTCGGTGGGCCAAGTGCTGGTCTTATGTTTACCTTGGCTATTTACGATCAGGTGTCTGGTCAAGACCTCAAGGCTGG
CCGCAAGATTGCTGGTACAGGAACTATTGAAAAAGATGGGGCTGTCGGTGATATCGGTGGGGCCTATCTCAAGGTGAAAT
CTGCGGCTGATAGTGGCGCAGACATTTTCTTCGTGCCAAATAATCTAGTAACTAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAGACTAATTATCAAGAGGCCAAGGAAGCTGCCGAGAAACTGGGGACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTTTTTGAAAAAGACTAAATGA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-206)

3D structure

• AlphaFold DB: A0A0E2QFS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	62.463	95.251	0.595