Detailed information NTG0510545

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STR1_RS05515
• Genome accession: NZ_CP065486
• Coordinates: 1060166..1061047 (-)
• Length: 293 a.a.
• NCBI ID: WP_022096754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain R1
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1055166..1066047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR1_RS05490 (STR1_05555)	vicR	1055875..1056582 (-)	708	WP_095559389.1	response regulator YycF	Regulator
STR1_RS05495 (STR1_05560)	-	1057104..1057871 (+)	768	WP_347128973.1	amino acid ABC transporter ATP-binding protein	-
STR1_RS05500 (STR1_05565)	-	1057883..1058716 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
STR1_RS05505 (STR1_05570)	-	1058734..1059432 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
STR1_RS05510 (STR1_05575)	-	1059444..1060094 (+)	651	WP_095559390.1	amino acid ABC transporter permease	-
STR1_RS05515 (STR1_05580)	endA	1060166..1061047 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
STR1_RS05520 (STR1_05585)	-	1061109..1061297 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STR1_RS05525 (STR1_05590)	murA	1061299..1062570 (-)	1272	WP_095559391.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STR1_RS05530 (STR1_05595)	-	1062640..1062876 (-)	237	WP_002946959.1	DUF1146 family protein	-
STR1_RS05535 (STR1_05600)	galE	1063065..1064078 (-)	1014	WP_095559392.1	UDP-glucose 4-epimerase GalE	-
STR1_RS05540	-	1064311..1064709 (-)	399	WP_309252125.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31813.61 Da
• Isoelectric Point: 10.1789

>NTDB_id=510545 STR1_RS05515 WP_022096754.1 1060166..1061047(-) (endA) [Streptococcus thermophilus strain R1]
MAKRKTSLTNKQKRQLVTLIIAVLIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSINSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510545 STR1_RS05515 WP_022096754.1 1060166..1061047(-) (endA) [Streptococcus thermophilus strain R1]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGTTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAATAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACAAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.635	86.007	0.608
endA	Streptococcus pneumoniae D39	70.635	86.007	0.608
endA	Streptococcus pneumoniae R6	70.635	86.007	0.608
endA	Streptococcus pneumoniae TIGR4	70.635	86.007	0.608