Detailed information NTG0510501

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: STMM20_RS08610
• Genome accession: NZ_CP065485
• Coordinates: 1692682..1693581 (-)
• Length: 299 a.a.
• NCBI ID: WP_011680720.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM20
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1687682..1698581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM20_RS08580	-	1687875..1688177 (+)	303	WP_347103542.1	hypothetical protein	-
STMM20_RS08585	-	1688418..1688702 (+)	285	WP_232557103.1	hypothetical protein	-
STMM20_RS08590	-	1688670..1688858 (-)	189	WP_224103239.1	hypothetical protein	-
STMM20_RS08595 (STMM20_08550)	-	1689089..1689657 (-)	569	Protein_1654	ATP-binding cassette domain-containing protein	-
STMM20_RS08600 (STMM20_08560)	-	1689875..1691053 (-)	1179	Protein_1655	IS256-like element IS1191 family transposase	-
STMM20_RS08605	-	1691147..1692507 (-)	1361	Protein_1656	peptide cleavage/export ABC transporter	-
STMM20_RS08610 (STMM20_08580)	comR	1692682..1693581 (-)	900	WP_011680720.1	helix-turn-helix domain-containing protein	Regulator
STMM20_RS08615 (STMM20_08585)	-	1693776..1694426 (-)	651	WP_011225447.1	phosphatase PAP2 family protein	-
STMM20_RS08620 (STMM20_08590)	-	1694429..1694986 (-)	558	WP_002949523.1	ECF transporter S component	-
STMM20_RS08625 (STMM20_08595)	-	1695298..1695807 (-)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
STMM20_RS08630 (STMM20_08600)	trkA	1696096..1697445 (+)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35271.71 Da
• Isoelectric Point: 5.1073

>NTDB_id=510501 STMM20_RS08610 WP_011680720.1 1692682..1693581(-) (comR) [Streptococcus thermophilus strain MM20]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=510501 STMM20_RS08610 WP_011680720.1 1692682..1693581(-) (comR) [Streptococcus thermophilus strain MM20]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTTTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMD-9	100	100	1
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.415