Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ST90728_RS01655 Genome accession   NZ_CP065479
Coordinates   298516..300033 (+) Length   505 a.a.
NCBI ID   WP_022096582.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 90728     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 293516..305033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST90728_RS01625 - 293808..293966 (+) 159 Protein_267 ascorbate 6-phosphate lactonase -
  ST90728_RS01630 (ST90728_01645) - 293983..294654 (-) 672 WP_002946492.1 TrkA family potassium uptake protein -
  ST90728_RS01635 (ST90728_01650) - 294694..296058 (-) 1365 WP_269473675.1 potassium transporter TrkG -
  ST90728_RS01640 (ST90728_01655) rsmG 296128..296841 (-) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ST90728_RS01645 (ST90728_01660) - 297138..297674 (+) 537 WP_002946488.1 YceD family protein -
  ST90728_RS01650 (ST90728_01665) covR 297830..298519 (+) 690 WP_002949638.1 response regulator transcription factor Regulator
  ST90728_RS01655 (ST90728_01670) covS 298516..300033 (+) 1518 WP_022096582.1 HAMP domain-containing histidine kinase Regulator
  ST90728_RS01660 (ST90728_01675) nrdR 300155..300634 (+) 480 WP_002949642.1 transcriptional regulator NrdR -
  ST90728_RS01665 (ST90728_01680) - 300631..301806 (+) 1176 WP_347114271.1 DnaD domain protein -
  ST90728_RS01670 (ST90728_01685) dnaI 301810..302712 (+) 903 WP_002946786.1 primosomal protein DnaI -
  ST90728_RS01675 (ST90728_01690) der 302818..304128 (+) 1311 WP_011680741.1 ribosome biogenesis GTPase Der -
  ST90728_RS01680 (ST90728_01695) - 304192..304861 (+) 670 Protein_278 HI_0552 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 57580.94 Da        Isoelectric Point: 5.1731

>NTDB_id=510111 ST90728_RS01655 WP_022096582.1 298516..300033(+) (covS) [Streptococcus thermophilus strain 90728]
MSKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLLAALY
SPKNIYPSIINGVLSEKRSLDGQVAVSNRLYSNQSVYVYDKKGTFIFTSEEDTDSPPGMSEVNKLKLVSYKGKRGFLLQV
PIYGKDKKTIVGYAQVFHDLEFYYALKERLIFLLIFLEVGMTVLVIAVTVVVLTSILRPMRQLHETMGIIIDSPSDLELR
SKIESHDEIGDLALNFNCMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHEANRM
TIMINDMLDSIRVKGSFDNHRNDTCDLNSSIRTVIGNFRVLHDDYQFYLNDSEGSDRPAQIYSQHFEQVITILIDNAVKY
SPVNKKIQITIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCHIDVSSE
LGVGTRFDLYIPFAESETTTPQIEG

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=510111 ST90728_RS01655 WP_022096582.1 298516..300033(+) (covS) [Streptococcus thermophilus strain 90728]
ATGAGTAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTTTCTTGTATTGTC
GATGTTCACTCTGGTTGTTGTATTTTCAGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAAATAATACAATCT
CAAAAGTTGTTACTTATATCGAAAAGGACTGGGACTCTGATGAAGAGTTGAGTCCAGAGCCGCTTTTAGCGGCCCTTTAT
TCACCGAAAAATATCTATCCATCAATCATTAATGGAGTGCTTTCTGAAAAGCGTTCCTTAGATGGTCAAGTTGCGGTTTC
TAATAGATTATATTCCAACCAGTCTGTCTATGTTTATGACAAAAAGGGAACTTTTATCTTTACTTCTGAGGAGGATACAG
ACTCACCTCCAGGCATGTCTGAGGTCAATAAACTGAAGTTGGTTTCCTATAAAGGTAAACGTGGTTTCTTACTACAAGTT
CCAATCTATGGCAAGGATAAGAAGACCATTGTTGGGTATGCTCAAGTTTTCCATGATTTGGAATTCTACTATGCGTTAAA
AGAGCGTTTAATTTTCCTATTGATATTCCTTGAAGTAGGAATGACGGTCTTAGTTATTGCAGTAACTGTAGTTGTCTTGA
CATCTATTCTTCGTCCGATGAGGCAGTTACACGAAACGATGGGTATTATTATCGATTCGCCAAGTGATTTGGAGCTTCGA
TCTAAGATTGAGAGTCATGATGAGATTGGTGATTTGGCACTTAACTTTAACTGTATGATGGATAAAATTCAAGAAAATAA
TCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCACGAATTACGTACTCCCATTGCAGTTATTAAAGGACATATGGACC
TCTTGCAACGTTGGGGTAAAAATGATCCTGAAATCCTTGAAGAAAGTCTTGAAGCTGCAAGTCACGAAGCCAACCGTATG
ACGATTATGATTAACGATATGTTGGATTCTATTCGTGTTAAAGGGTCATTTGACAATCATAGAAATGATACATGTGATTT
GAATTCTTCAATCCGTACGGTTATTGGGAATTTTCGTGTCCTACATGACGACTACCAATTCTACCTCAATGATTCTGAGG
GTTCAGATCGTCCAGCACAGATTTACAGCCAGCACTTTGAACAGGTTATTACTATTTTGATTGATAATGCGGTCAAGTAT
TCGCCTGTTAATAAGAAAATCCAGATTACTATCAAGGCTCTGGAAGATGAGATGCTGGTACAGGTACAGGATAATGGTGA
GGGTATCTCTAAAGAAGATATTGAACATATATTTGAACGCTTCTATCGTTCAGATAAGGCGCGTAATCGTACGACAACCC
AATCTGGTGTGGGTATTGGTTTATCAATCCTCTATCAAATTGTGGAAGCTTATCGATGCCATATCGATGTCAGTTCAGAA
CTTGGTGTGGGTACACGTTTTGACCTCTACATTCCTTTTGCAGAGTCAGAAACTACGACACCTCAAATTGAAGGTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(384-494)

ArlS sensor domain (ArlS_N)

(39-187)

His Kinase A (phospho-acceptor) domain (HisKA)

(270-329)

HAMP domain (HAMP)

(213-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

94.821

99.406

0.943