Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KU540_RS05895 Genome accession   NZ_CP077894
Coordinates   1214029..1214745 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   P0A0I7
Organism   Staphylococcus aureus strain 329     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1209029..1219745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU540_RS05875 (KU540_05840) - 1210121..1211071 (+) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -
  KU540_RS05880 (KU540_05845) - 1211220..1212704 (+) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  KU540_RS05885 (KU540_05850) - 1212701..1213660 (+) 960 WP_001253296.1 carbohydrate kinase family protein -
  KU540_RS05890 (KU540_05855) - 1213850..1213957 (-) 108 WP_031785433.1 hypothetical protein -
  KU540_RS05895 (KU540_05860) agrA 1214029..1214745 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KU540_RS05900 (KU540_05865) agrC 1214764..1216056 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  KU540_RS05905 (KU540_05870) agrD 1216081..1216221 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  KU540_RS05910 (KU540_05875) agrB 1216218..1216787 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  KU540_RS14340 hld 1217077..1217157 (+) 81 WP_000046022.1 delta-hemolysin -
  KU540_RS05920 (KU540_05885) - 1217757..1218542 (-) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  KU540_RS05925 (KU540_05890) - 1219012..1219638 (-) 627 WP_000522375.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=510100 KU540_RS05895 WP_000688492.1 1214029..1214745(-) (agrA) [Staphylococcus aureus strain 329]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=510100 KU540_RS05895 WP_000688492.1 1214029..1214745(-) (agrA) [Staphylococcus aureus strain 329]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3BS1
  PDB 4G4K

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1