Detailed information
Bioinformatically predicted
Overview
| Name | clpE | Type | Regulator |
| Locus tag | ST4134_RS03080 | Genome accession | NZ_CP065478 |
| Coordinates | 572669..574927 (-) | Length | 752 a.a. |
| NCBI ID | WP_014621345.1 | Uniprot ID | A0A8D6XQT7 |
| Organism | Streptococcus thermophilus strain 4134 | ||
| Function | repress competence development (at the early growth phase) (predicted from homology) Competence regulation |
||
Genomic Context
Location: 567669..579927
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ST4134_RS03050 (ST4134_03045) | - | 568065..568685 (+) | 621 | WP_023909511.1 | DUF3862 domain-containing protein | - |
| ST4134_RS03055 (ST4134_03050) | - | 568898..569440 (+) | 543 | WP_014621342.1 | TVP38/TMEM64 family protein | - |
| ST4134_RS03060 (ST4134_03055) | - | 569418..570653 (+) | 1236 | WP_002950192.1 | aminoacyltransferase | - |
| ST4134_RS03065 (ST4134_03060) | - | 570752..571715 (+) | 964 | Protein_541 | Gfo/Idh/MocA family protein | - |
| ST4134_RS03070 (ST4134_03065) | - | 571756..572058 (-) | 303 | WP_014608115.1 | DUF1827 family protein | - |
| ST4134_RS03075 (ST4134_03070) | - | 572068..572526 (-) | 459 | WP_002947302.1 | NUDIX hydrolase | - |
| ST4134_RS03080 (ST4134_03075) | clpE | 572669..574927 (-) | 2259 | WP_014621345.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| ST4134_RS03085 (ST4134_03080) | argF | 575168..576148 (+) | 981 | WP_014608116.1 | ornithine carbamoyltransferase | - |
| ST4134_RS03090 (ST4134_03085) | - | 576217..576447 (+) | 231 | WP_011225686.1 | DUF1797 family protein | - |
| ST4134_RS03095 (ST4134_03090) | - | 576718..577398 (+) | 681 | WP_014608117.1 | amino acid ABC transporter permease | - |
| ST4134_RS03100 (ST4134_03095) | - | 577398..578132 (+) | 735 | WP_011225688.1 | amino acid ABC transporter ATP-binding protein | - |
| ST4134_RS03105 (ST4134_03100) | - | 578306..578782 (+) | 477 | WP_024704027.1 | ferrous iron transport protein A | - |
Sequence
Protein
Download Length: 752 a.a. Molecular weight: 83806.94 Da Isoelectric Point: 5.2102
>NTDB_id=510061 ST4134_RS03080 WP_014621345.1 572669..574927(-) (clpE) [Streptococcus thermophilus strain 4134]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQSPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDF
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQSPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKDF
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN
Nucleotide
Download Length: 2259 bp
>NTDB_id=510061 ST4134_RS03080 WP_014621345.1 572669..574927(-) (clpE) [Streptococcus thermophilus strain 4134]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAATCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATTTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAATCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGTGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATTTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpE | Streptococcus mutans UA159 |
84.288 |
99.867 |
0.842 |
| clpE | Streptococcus pneumoniae Rx1 |
82.048 |
100 |
0.82 |
| clpE | Streptococcus pneumoniae D39 |
82.048 |
100 |
0.82 |
| clpE | Streptococcus pneumoniae R6 |
82.048 |
100 |
0.82 |
| clpE | Streptococcus pneumoniae TIGR4 |
81.915 |
100 |
0.819 |
| clpC | Lactococcus lactis subsp. cremoris KW2 |
76.368 |
99.601 |
0.761 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
51.772 |
86.303 |
0.447 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
46.037 |
87.234 |
0.402 |
| clpC | Streptococcus pneumoniae Rx1 |
46.984 |
83.777 |
0.394 |
| clpC | Streptococcus pneumoniae D39 |
46.984 |
83.777 |
0.394 |
| clpC | Streptococcus pneumoniae TIGR4 |
46.825 |
83.777 |
0.392 |
| clpC | Streptococcus mutans UA159 |
46.326 |
83.245 |
0.386 |
| clpC | Streptococcus thermophilus LMD-9 |
46.4 |
83.112 |
0.386 |
| clpC | Streptococcus thermophilus LMG 18311 |
46.08 |
83.112 |
0.383 |