Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ST4134_RS02970 Genome accession   NZ_CP065478
Coordinates   553062..554288 (+) Length   408 a.a.
NCBI ID   WP_024704025.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4134     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 548062..559288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4134_RS02945 (ST4134_02940) - 548637..549908 (-) 1272 WP_011680901.1 hydroxymethylglutaryl-CoA reductase, degradative -
  ST4134_RS02950 (ST4134_02945) - 549901..551076 (-) 1176 WP_011680902.1 hydroxymethylglutaryl-CoA synthase -
  ST4134_RS02955 (ST4134_02950) - 551398..552258 (+) 861 WP_002950145.1 thymidylate synthase -
  ST4134_RS02960 (ST4134_02955) - 552366..552869 (+) 504 WP_002950147.1 dihydrofolate reductase -
  ST4134_RS02965 (ST4134_02960) - 552874..553044 (+) 171 WP_002886174.1 hypothetical protein -
  ST4134_RS02970 (ST4134_02965) clpX 553062..554288 (+) 1227 WP_024704025.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ST4134_RS02975 (ST4134_02970) yihA 554298..554897 (+) 600 WP_011680905.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ST4134_RS02980 (ST4134_02975) - 555027..556403 (+) 1377 WP_024704026.1 amino acid permease -
  ST4134_RS02985 (ST4134_02980) mmuM 556415..557365 (+) 951 WP_011680907.1 homocysteine S-methyltransferase -
  ST4134_RS02990 (ST4134_02985) - 557478..557732 (+) 255 WP_002950164.1 DUF1912 family protein -
  ST4134_RS02995 (ST4134_02990) - 557804..558163 (+) 360 WP_011226993.1 helix-hairpin-helix domain-containing protein -
  ST4134_RS03000 (ST4134_02995) plsY 558277..558918 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45086.53 Da        Isoelectric Point: 4.4429

>NTDB_id=510060 ST4134_RS02970 WP_024704025.1 553062..554288(+) (clpX) [Streptococcus thermophilus strain 4134]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDHDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLATLEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=510060 ST4134_RS02970 WP_024704025.1 553062..554288(+) (clpX) [Streptococcus thermophilus strain 4134]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATCATGATGTGGA
CTTGCAAAAATCAAATATTCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTTGCGACCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTCTGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.509

100

0.887
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566