Detailed information NTG0510010

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST4078_RS05430
• Genome accession: NZ_CP065477
• Coordinates: 1022784..1023665 (-)
• Length: 293 a.a.
• NCBI ID: WP_014608376.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4078
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1017784..1028665

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4078_RS05405 (ST4078_05380)	vicR	1018488..1019195 (-)	708	WP_011681206.1	response regulator YycF	Regulator
ST4078_RS05410 (ST4078_05385)	-	1019722..1020489 (+)	768	WP_014608372.1	amino acid ABC transporter ATP-binding protein	-
ST4078_RS05415 (ST4078_05390)	-	1020501..1021334 (+)	834	WP_014608373.1	transporter substrate-binding domain-containing protein	-
ST4078_RS05420 (ST4078_05395)	-	1021352..1022050 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
ST4078_RS05425 (ST4078_05400)	-	1022062..1022712 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
ST4078_RS05430 (ST4078_05405)	endA	1022784..1023665 (-)	882	WP_014608376.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4078_RS05435 (ST4078_05410)	-	1023727..1023915 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST4078_RS05440 (ST4078_05415)	murA	1023917..1025188 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4078_RS05445 (ST4078_05420)	-	1025258..1025494 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST4078_RS05450 (ST4078_05425)	galE	1025682..1026695 (-)	1014	WP_014608379.1	UDP-glucose 4-epimerase GalE	-
ST4078_RS05455 (ST4078_05430)	-	1026710..1027213 (-)	504	WP_224102963.1	DUF4832 domain-containing protein	-
ST4078_RS05460 (ST4078_05435)	-	1027203..1027655 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31774.44 Da
• Isoelectric Point: 10.0477

>NTDB_id=510010 ST4078_RS05430 WP_014608376.1 1022784..1023665(-) (endA) [Streptococcus thermophilus strain 4078]
MAKRETSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510010 ST4078_RS05430 WP_014608376.1 1022784..1023665(-) (endA) [Streptococcus thermophilus strain 4078]
ATGGCAAAAAGAGAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594