Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   SCR2_RS03215 Genome accession   NC_022245
Coordinates   640722..644402 (+) Length   1226 a.a.
NCBI ID   WP_020997711.1    Uniprot ID   U2YA87
Organism   Streptococcus constellatus subsp. pharyngis C818     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 635722..649402
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCR2_RS03205 (SCR2_0634) - 636115..637329 (+) 1215 WP_006267100.1 ABC transporter permease -
  SCR2_RS03210 (SCR2_0635) rexB 637450..640725 (+) 3276 WP_006267494.1 ATP-dependent nuclease subunit B Machinery gene
  SCR2_RS03215 (SCR2_0636) rexA 640722..644402 (+) 3681 WP_020997711.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  SCR2_RS03220 (SCR2_0637) glgB 644872..646782 (+) 1911 WP_006267608.1 1,4-alpha-glucan branching protein GlgB -
  SCR2_RS03225 (SCR2_0638) - 646786..647928 (+) 1143 WP_003025294.1 glucose-1-phosphate adenylyltransferase -
  SCR2_RS03230 (SCR2_0639) glgD 647918..649057 (+) 1140 WP_020997712.1 glucose-1-phosphate adenylyltransferase subunit GlgD -

Sequence

Protein


Download         Length: 1226 a.a.        Molecular weight: 141556.55 Da        Isoelectric Point: 5.6332

>NTDB_id=50993 SCR2_RS03215 WP_020997711.1 640722..644402(+) (rexA) [Streptococcus constellatus subsp. pharyngis C818]
MRQIPFLTQAEIRALQDQEVQSDKVQKRTVEQIEAIYSSGQNILVSASAGSGKTFVMVQRIIDQIMRGVRIEQLFISTFT
VKAASELKERLEKELSKALKETNDEELKQHLAQQLADIPNADIGTMDSFTQKVLNKYGYLLELAPNFRILQNASEQLLLQ
NEVFEQVFEDFYQSDQATLFKKLVKNFTGQRKDLLGFREQVYKIYSFLQSTSSPIEWLEKDFLKGYEFADFQEEKAQLLA
QTKEALFDLEDFFSYHLVHEAKEFPKARYLENVQRVLDDLASLQGQSSEEAYLTALNNIVEISRVSNGKALTNSGRKEEL
KEIINAYNEKRKEKIQVLRDLADQFYRFEFQLTYHEEAKEILLVLQQFMKLFVTSYLNRKKEENAFEFTDISHFAIQILE
ECSDVRQFYRNKYHEVMVDEYQDTNHTQERMLELLSNGDNRFMVGDIKQSIYRFRQADPQIFNEKFKTYKEDSRQGKLIV
LKENFRSHLEVLEATNDVFKRLMDEEVGEIDYNETHYLVAGNPDKKEPNPLYQTEFLIYDGALEADKEENDKEVSSVSAG
EVELVIKEIIRLYNEENVQFEDITLLTASRTRNDVILAEFAKYGIPVVSDGGEDNYLQSVEVMVMLDTLRTINNPLNDYA
LVALLKSPMFNFTEDELARLALQKKVTETNYVVHQENLYEKLKNALNGYGQYPELITPPLLKKIQQFQGTLQAWREYAKT
NSLYDLLWKIYQDRFYYDYVGALPNGAGRQANLYALTLRANDYEKMSFKGLSRFIGMIDKILETQNDLASVVSAAPKHAV
RLMTVHKSKGLEFKYVFLLNMDKVFNRKDSSSALILSRQNGVGIKYVADVAVDVADKLAPNHVRLSIDTLPYEQNEREIH
LASISEQMRLLYVAMTRAERKLYLVGKGHKNSLEKKSFPTPVKGHLAASIRQSMTSFQDWMWTLHVVFEKDNLAFSTRFV
TDSDLTSEKIGQLKLKHAVIEEDLIDNRQSEDIRRALDILENVDRLNTKYQAAIRLPSVRTPSQIKKFYEPIMDTDGVEI
MEKRNPTIVGKASFELPNFAKKAPVTGAQIGSAVHELMQRIPLVQAPTIAILRKVLKQVQAEESVKKKIDLQKIASFFGT
ELGQLLLKHTDRVYREAPFAMLKQDPASGQYFVVRGILDGYLLLTDRIILFDYKTDRYTNPSELVERYQAQLALYAEALS
RSYSIEKVEKYLVLLGGAQLQVVKVE

Nucleotide


Download         Length: 3681 bp        

>NTDB_id=50993 SCR2_RS03215 WP_020997711.1 640722..644402(+) (rexA) [Streptococcus constellatus subsp. pharyngis C818]
ATGAGACAAATTCCATTTTTGACTCAAGCAGAGATTCGTGCTTTGCAGGATCAGGAAGTTCAGTCTGACAAAGTTCAAAA
ACGTACAGTAGAACAGATTGAAGCCATTTACTCTTCCGGTCAAAATATTCTGGTTTCTGCTTCTGCGGGATCAGGAAAAA
CCTTTGTTATGGTGCAGCGGATTATTGACCAAATTATGCGGGGAGTTCGTATTGAGCAGCTCTTCATTTCAACTTTCACC
GTCAAAGCAGCTAGTGAATTAAAAGAGCGCTTGGAGAAAGAGCTGTCCAAGGCTTTGAAAGAAACAAATGATGAGGAACT
TAAACAACACTTGGCTCAGCAATTAGCCGATATTCCGAATGCAGATATTGGAACCATGGACTCTTTTACCCAAAAAGTCC
TGAATAAATATGGTTATCTATTGGAATTGGCGCCAAATTTTCGCATTTTGCAAAATGCGAGTGAGCAGTTATTGCTACAA
AACGAAGTTTTTGAGCAAGTTTTTGAAGACTTCTATCAATCTGATCAGGCTACTTTGTTTAAAAAATTAGTCAAAAACTT
TACAGGTCAGAGAAAAGATTTGCTTGGTTTTCGCGAGCAGGTTTATAAGATTTATTCTTTCTTGCAGTCTACTAGTAGTC
CAATAGAATGGTTGGAAAAAGACTTTTTGAAAGGCTATGAGTTTGCAGATTTCCAAGAAGAAAAAGCGCAACTTTTAGCA
CAAACAAAAGAAGCCCTCTTTGATTTAGAAGATTTTTTTAGCTATCATTTGGTTCATGAAGCCAAGGAATTTCCCAAAGC
AAGATATCTTGAAAATGTGCAGCGTGTGCTTGATGACCTGGCAAGCTTACAAGGACAATCCTCTGAGGAAGCCTATCTCA
CAGCGCTCAATAACATTGTAGAAATATCGCGGGTCAGCAATGGGAAAGCCTTGACGAACAGCGGACGAAAAGAAGAATTA
AAAGAAATTATCAACGCCTATAACGAAAAACGCAAAGAAAAAATTCAAGTTTTACGAGACTTGGCAGATCAATTTTATCG
TTTTGAATTTCAATTGACCTACCATGAGGAAGCAAAAGAAATTTTACTTGTTTTGCAACAATTTATGAAATTGTTTGTTA
CAAGCTATTTGAATCGCAAAAAAGAAGAAAATGCTTTTGAATTTACGGACATTAGTCATTTTGCTATTCAGATCTTAGAA
GAATGTTCGGATGTGCGTCAGTTTTATAGGAACAAATACCATGAAGTTATGGTAGATGAATATCAAGATACTAACCACAC
GCAAGAGCGGATGCTAGAACTGTTATCAAATGGGGATAATCGCTTTATGGTGGGGGATATTAAACAGTCTATTTACCGTT
TTCGTCAAGCGGATCCGCAGATTTTCAATGAGAAATTCAAAACCTATAAAGAAGATAGCAGACAAGGAAAATTGATTGTT
TTAAAAGAGAATTTTCGCAGTCATTTGGAAGTCTTGGAAGCCACCAATGATGTGTTTAAGCGCCTCATGGATGAGGAAGT
GGGAGAAATTGATTACAATGAAACGCATTATCTGGTCGCTGGAAATCCTGATAAAAAAGAACCAAATCCCTTGTATCAGA
CAGAATTTCTCATTTATGATGGAGCGCTTGAAGCGGATAAGGAGGAGAATGACAAGGAGGTTTCTTCTGTTTCTGCAGGA
GAAGTAGAACTGGTAATTAAAGAAATTATTCGCCTGTACAATGAAGAAAATGTCCAATTTGAGGATATTACTTTGCTAAC
GGCTTCGCGGACGCGCAACGATGTGATTTTAGCTGAATTTGCTAAATATGGTATTCCTGTCGTTTCAGACGGTGGTGAGG
ACAATTACCTTCAGTCTGTTGAAGTCATGGTGATGTTAGACACCTTGCGTACAATTAACAACCCTCTCAATGATTATGCT
TTAGTGGCGCTTTTAAAATCGCCAATGTTTAACTTTACAGAAGATGAATTGGCACGTTTAGCTTTGCAAAAGAAGGTGAC
TGAGACAAATTATGTTGTCCATCAGGAAAATCTCTATGAGAAGTTGAAGAATGCTCTGAATGGGTACGGGCAATATCCTG
AACTTATCACGCCTCCTCTTTTAAAAAAAATCCAGCAATTTCAAGGAACACTACAGGCTTGGCGAGAGTATGCAAAAACA
AATTCACTATATGATTTGCTTTGGAAAATTTATCAAGATCGCTTTTATTACGATTATGTGGGAGCTTTACCAAATGGAGC
GGGACGTCAAGCTAATCTCTATGCCCTTACTTTGCGCGCAAATGATTACGAAAAAATGAGTTTTAAAGGCTTGTCACGTT
TTATCGGGATGATTGATAAAATCTTGGAAACACAGAATGATTTAGCTAGTGTAGTTAGTGCAGCTCCGAAACATGCGGTT
CGCCTGATGACGGTTCATAAGAGCAAAGGTTTGGAATTTAAATATGTCTTTTTGCTCAATATGGACAAAGTATTTAATCG
TAAAGATAGCAGTTCCGCTTTGATTCTCAGTCGTCAAAATGGTGTTGGAATCAAGTATGTGGCTGATGTAGCAGTAGATG
TTGCTGATAAGTTAGCTCCAAACCATGTTCGTTTGTCTATTGATACTCTGCCTTATGAGCAAAATGAACGTGAGATTCAT
TTAGCCAGCATTTCGGAACAAATGCGTCTACTCTATGTCGCCATGACACGCGCTGAAAGGAAACTGTATTTAGTTGGTAA
AGGTCATAAGAACAGTTTGGAGAAAAAAAGCTTCCCTACTCCAGTGAAGGGGCATTTAGCTGCATCTATCAGGCAAAGTA
TGACAAGTTTTCAAGATTGGATGTGGACTTTACATGTAGTATTTGAGAAAGATAATCTAGCTTTTTCAACGCGATTTGTG
ACAGATAGTGACTTGACAAGTGAAAAAATAGGTCAACTGAAATTGAAACATGCGGTTATTGAAGAGGATTTAATAGACAA
TCGCCAATCTGAGGATATTCGTAGGGCTTTGGATATTTTGGAAAATGTAGATCGACTGAATACCAAGTATCAAGCTGCCA
TCCGTTTACCGAGTGTTCGAACACCGAGTCAAATTAAGAAATTTTATGAACCGATTATGGATACAGACGGCGTTGAAATT
ATGGAGAAAAGGAATCCGACCATTGTAGGAAAAGCTTCTTTTGAGCTACCAAATTTTGCTAAAAAAGCTCCAGTTACAGG
AGCGCAAATCGGTAGCGCTGTCCATGAACTGATGCAGCGTATTCCTTTGGTTCAAGCCCCTACGATAGCTATTTTGAGAA
AAGTTTTAAAACAGGTTCAGGCAGAAGAAAGTGTTAAAAAGAAAATTGATTTGCAAAAGATAGCTAGTTTTTTTGGGACT
GAACTTGGGCAGCTCCTTTTGAAGCATACAGACAGAGTATATCGTGAAGCTCCTTTTGCTATGTTAAAGCAGGATCCAGC
AAGTGGACAATATTTTGTAGTCCGTGGGATTCTGGACGGTTATCTACTGCTGACGGACCGAATCATTCTCTTTGATTACA
AGACGGATCGATATACAAATCCAAGTGAATTAGTGGAGCGCTACCAAGCACAATTAGCACTTTATGCTGAAGCTCTTAGT
CGTTCATACAGTATTGAAAAAGTTGAAAAATACTTAGTGTTGTTAGGCGGAGCACAGCTTCAAGTGGTGAAAGTAGAATA
G

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(30-469)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1068-1203)

UvrD-like helicase C-terminal domain (UvrD_C)

(479-904)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2YA87

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

60.408

99.918

0.604

Multiple sequence alignment