Detailed information NTG0509579

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: I5W22_RS07795
• Genome accession: NZ_CP065431
• Coordinates: 1575612..1576661 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain YP20190405
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1570612..1581661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I5W22_RS07775 (I5W22_07775)	nadE	1571018..1571842 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
I5W22_RS07780 (I5W22_07780)	-	1573138..1573665 (-)	528	WP_012027591.1	VanZ family protein	-
I5W22_RS07785 (I5W22_07785)	rlmN	1573662..1574774 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
I5W22_RS07790 (I5W22_07790)	-	1574783..1575424 (-)	642	WP_012027595.1	YutD family protein	-
I5W22_RS07795 (I5W22_07795)	sepM	1575612..1576661 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
I5W22_RS07800 (I5W22_07800)	coaD	1576648..1577136 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
I5W22_RS07805 (I5W22_07805)	rsmD	1577126..1577665 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I5W22_RS07810 (I5W22_07810)	-	1577973..1578695 (-)	723	WP_012027598.1	lipoprotein	-
I5W22_RS07815 (I5W22_07815)	-	1578752..1579138 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
I5W22_RS07820 (I5W22_07820)	-	1579138..1579356 (-)	219	WP_004194736.1	YqgQ family protein	-
I5W22_RS07825 (I5W22_07825)	-	1579664..1580266 (-)	603	WP_012027601.1	response regulator transcription factor	-
I5W22_RS07830 (I5W22_07830)	-	1580263..1581357 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=509579 I5W22_RS07795 WP_012775295.1 1575612..1576661(-) (sepM) [Streptococcus suis strain YP20190405]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=509579 I5W22_RS07795 WP_012775295.1 1575612..1576661(-) (sepM) [Streptococcus suis strain YP20190405]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605