Detailed information NTG0050951

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SAIN_RS09005
• Genome accession: NC_022244
• Coordinates: 1821082..1823643 (-)
• Length: 853 a.a.
• NCBI ID: WP_021002205.1
• Uniprot ID: -
• Organism: Streptococcus anginosus C1051
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1816082..1828643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAIN_RS08980 (SAIN_1750)	ruvA	1816163..1816753 (-)	591	WP_021002202.1	Holliday junction branch migration protein RuvA	Machinery gene
SAIN_RS08985 (SAIN_1751)	-	1816915..1817424 (+)	510	WP_003026648.1	helix-turn-helix domain-containing protein	-
SAIN_RS08990 (SAIN_1752)	hexB	1817807..1819753 (-)	1947	WP_003026650.1	DNA mismatch repair endonuclease MutL	Machinery gene
SAIN_RS08995 (SAIN_1753)	brsR	1819998..1820438 (+)	441	WP_041784066.1	LytTR family DNA-binding domain-containing protein	Regulator
SAIN_RS09000 (SAIN_1754)	-	1820435..1820893 (+)	459	WP_021002204.1	DUF3021 domain-containing protein	-
SAIN_RS09005 (SAIN_1755)	hexA	1821082..1823643 (-)	2562	WP_021002205.1	DNA mismatch repair protein MutS	Machinery gene
SAIN_RS09010 (SAIN_1756)	argR	1823806..1824246 (-)	441	WP_003027809.1	arginine repressor	-
SAIN_RS09015 (SAIN_1757)	argS	1824350..1826038 (+)	1689	WP_021002206.1	arginine--tRNA ligase	-
SAIN_RS09020 (SAIN_1758)	nrdI	1826093..1826548 (-)	456	WP_021002207.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
SAIN_RS09025 (SAIN_1759)	-	1826624..1827133 (-)	510	WP_003026664.1	hypothetical protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96088.83 Da
• Isoelectric Point: 5.0392

>NTDB_id=50951 SAIN_RS09005 WP_021002205.1 1821082..1823643(-) (hexA) [Streptococcus anginosus C1051]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNM
VCGEIRNLRTREVVLGYELSEMERQVLEIQMNLLLSQVETTFDDVQLLGKDLSPLERQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELANLIQLAISP
DAPNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAHTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNQTGAKTLFATHYHEL
TELSTSLTQLENVHVATLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQANEKSSFGISNTL
PADAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=50951 SAIN_RS09005 WP_021002205.1 1821082..1823643(-) (hexA) [Streptococcus anginosus C1051]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGCTATT
TCGTATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAATCCAATCCCGATGGCAGGAGTTCCCTACCATTCGGTGCAACAGTATATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGGCTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATG
GTCTGTGGAGAAATCCGAAACTTGCGAACGCGTGAAGTGGTCTTAGGGTATGAATTGTCTGAAATGGAGCGCCAAGTATT
GGAGATTCAAATGAATCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCGC
CGCTAGAGCGCCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGATTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGAGACTAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAACGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCGAAAGATCTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAATTGGCAAACTTGATTCAGTTGGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGACAAGTATCGAGTGGTCAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACCAATTCTCAGCTTGAACATGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTTTGAAAAATTCGGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGTGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
ACACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCAGAAAAGCAACATTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTATATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCCGAAAGTGCCCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGGTGGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCTACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCAGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGCAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTGCGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (255-546)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.553	100	0.766
mutS	Pseudomonas stutzeri strain ATCC 17587	36.121	100	0.365