Detailed information NTG0509078

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: KU528_RS10625
• Genome accession: NZ_CP077865
• Coordinates: 2161540..2164386 (+)
• Length: 948 a.a.
• NCBI ID: WP_225805720.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 370
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2156540..2169386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KU528_RS10600 (KU528_10555)	-	2157127..2157234 (+)	108	WP_001790093.1	hypothetical protein	-
KU528_RS10605 (KU528_10560)	-	2157382..2158221 (+)	840	WP_000749391.1	COG3942 and LysM peptidoglycan-binding domain-containing protein	-
KU528_RS10610 (KU528_10565)	-	2158395..2159045 (+)	651	WP_000538141.1	YfbR-like 5'-deoxynucleotidase	-
KU528_RS10615 (KU528_10570)	-	2159042..2159278 (+)	237	WP_000638418.1	CsbA family protein	-
KU528_RS10620 (KU528_10575)	uvrB	2159547..2161532 (+)	1986	WP_000229251.1	excinuclease ABC subunit UvrB	Machinery gene
KU528_RS10625 (KU528_10580)	uvrA	2161540..2164386 (+)	2847	WP_225805720.1	excinuclease ABC subunit UvrA	Machinery gene
KU528_RS10630 (KU528_10585)	hprK	2164996..2165928 (+)	933	WP_000958224.1	HPr(Ser) kinase/phosphatase	-
KU528_RS10635 (KU528_10590)	lgt	2165934..2166773 (+)	840	WP_000513315.1	prolipoprotein diacylglyceryl transferase	-
KU528_RS10640 (KU528_10595)	-	2166781..2167266 (+)	486	WP_001224799.1	acyltransferase	-
KU528_RS10645 (KU528_10600)	-	2167274..2168713 (+)	1440	WP_000057560.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 948 a.a.
• Molecular weight: 105363.19 Da
• Isoelectric Point: 6.3740

>NTDB_id=509078 KU528_RS10625 WP_225805720.1 2161540..2164386(+) (uvrA) [Staphylococcus aureus strain 370]
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEG
LSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPILDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVID
GEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTL
LKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKY
MTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTL
NRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDI
GPGAGEHGGQIVSSGAPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGV
SGSGKSSLVNEVLYKSLAQKINKSKLKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAK
IRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFEN
IPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENG
DTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK

Nucleotide

• Length: 2847 bp

>NTDB_id=509078 KU528_RS10625 WP_225805720.1 2161540..2164386(+) (uvrA) [Staphylococcus aureus strain 370]
ATGAAAGAACCATCCATAGTAGTAAAAGGTGCTCGTGCGCATAACTTGAAAGATATTGATATCGAACTACCTAAAAATAA
ATTAATTGTTATGACAGGTTTATCTGGGTCAGGTAAATCGTCATTAGCATTCGATACTATATATGCTGAAGGACAACGAC
GTTATGTTGAATCATTAAGTGCCTATGCGCGTCAATTTTTAGGCCAAATGGACAAACCAGATGTTGATACAATTGAAGGA
TTATCGCCAGCAATTTCAATAGATCAAAAAACAACAAGTAAAAATCCAAGATCAACTGTAGCAACAGTAACAGAAATATA
TGATTATATACGTTTGTTATATGCACGCGTTGGTAAACCTTACTGTCCAAATCACAATATAGAAATTGAATCGCAAACAG
TACAACAAATGGTTGACCGCATTATGGAATTAGAGGCACGTACAAAGATTCAATTATTAGCACCTGTCATCGCTCATCGT
AAAGGTAGTCATGAAAAGCTAATCGAAGATATTGGTAAAAAAGGTTATGTACGTTTAAGAATCGATGGCGAAATTGTTGA
TGTAAATGATGTACCTATATTAGATAAGAACAAGAATCATACAATAGAAGTTGTTGTAGACCGATTAGTTGTTAAAGATG
GAATTGAAACACGACTAGCTGACTCTATAGAAACTGCGTTAGAGCTTTCAGAAGGACAATTAACAGTTGATGTTATTGAC
GGGGAAGACCTTAAGTTTTCAGAAAGCCACGCTTGTCCTATATGTGGATTTTCAATCGGAGAATTAGAACCAAGAATGTT
TAGCTTTAACAGTCCTTTTGGTGCTTGTCCAACATGTGATGGCTTAGGGCAAAAGTTAACAGTCGATGTAGACTTGGTTG
TTCCTGACAAAGATAAGACACTAAACGAAGGTGCAATAGAACCTTGGATACCGACGAGTTCTGATTTTTATCCAACATTG
TTAAAACGTGTTTGTGAAGTTTATAAAATCAATATGGATAAACCTTTTAAAAAGTTAACAGAACGTCAACGTGATATTTT
ATTGTATGGTTCGGGTGACAAAGAAATTGAATTTACATTTACACAACGTCAAGGTGGTACTAGAAAACGAACAATGGTCT
TCGAGGGTGTAGTTCCTAATATAAGTAGACGATTCCACGAATCACCTTCAGAATATACACGTGAAATGATGAGTAAATAT
ATGACCGAACTACCTTGCGAAACTTGTCATGGAAAGCGATTGAGTCGTGAAGCGTTATCTGTTTATGTAGGTGGTTTAAA
TATTGGTGAAGTAGTCGAATACTCAATCAGTCAAGCGCTGAACTATTATAAAAACATTAATTTGTCAGAACAAGATCAAG
CGATTGCAAATCAAATATTGAAAGAAATTATTTCTCGACTCACTTTTTTAAATAATGTGGGACTTGAATATTTAACGCTA
AACAGAGCTTCAGGTACACTTTCAGGTGGTGAAGCACAACGTATTCGATTAGCAACGCAAATTGGGTCACGTTTGACTGG
TGTCTTATATGTATTAGATGAGCCATCAATTGGACTGCATCAAAGAGATAATGATCGATTAATTAATACACTTAAAGAAA
TGAGAGATTTAGGAAATACTTTAATTGTAGTTGAACACGATGATGATACAATGCGTGCGGCTGATTACTTAGTGGACATA
GGGCCTGGTGCTGGTGAGCATGGAGGACAGATTGTGTCTAGTGGTGCACCTCAAAAGGTAATGAAAGATAAAAAATCTTT
AACAGGACAATACTTGAGTGGTAAGAAACGTATTGAAGTACCTGAATATCGCAGACCGGCTTCAGATCGTAAAATTTCTA
TACGTGGAGCTAGAAGTAACAACCTTAAAGGGGTTGATGTGGACATACCACTATCAATCATGACGGTCGTTACAGGTGTA
TCAGGTTCAGGTAAAAGCTCATTAGTAAATGAAGTATTATACAAATCATTAGCTCAAAAAATCAATAAATCTAAATTAAA
GCCAGGATTGTACGATAAGATTGAAGGTATTGATCAACTTGATAAAATTATTGATATTGATCAATCACCGATAGGTAGAA
CGCCACGCTCTAATCCAGCAACGTATACTGGTGTGTTTGATGATATACGTGATGTGTTTGCGCAAACAAATGAAGCTAAA
ATTCGAGGATATCAAAAAGGCCGTTTTAGTTTTAATGTAAAAGGTGGACGCTGTGAAGCTTGTAAAGGTGACGGTATTAT
TAAGATTGAAATGCATTTTTTACCTGATGTTTATGTTCCTTGTGAAGTGTGTGATGGTAAACGATATAATCGTGAGACAC
TAGAGGTTACTTACAAAGGTAAAAATATTGCTGACATTTTAGAAATGACTGTTGAAGAGGCAACACAATTTTTTGAAAAC
ATTCCTAAGATTAAGCGCAAGCTACAAACACTAGTTGATGTTGGTCTTGGATACGTCACATTAGGTCAACAAGCTACAAC
GTTATCAGGTGGTGAGGCTCAACGTGTGAAACTTGCATCTGAACTTCATAAACGTTCAACTGGTAAATCTATTTATATCC
TAGACGAACCGACAACAGGGTTACATGTTGACGATATTAGTAGATTATTAAAAGTATTAAACCGATTAGTTGAAAATGGT
GATACTGTTGTAATTATTGAACATAACCTAGATGTTATCAAAACAGCAGACTATATTATAGACTTAGGTCCTGAAGGTGG
TAGTGGCGGTGGTACTATTGTTGCGACTGGCACACCTGAAGATATTGCTCAGACAAAGTCATCATATACAGGAAAGTATT
TAAAAGAAGTACTTGAACGAGATAAACAAAATACTGAAGATAAATAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-399)

• ABC transporter (ABC_tran) (622-858)

• UvrA interaction domain (UvrA_inter) (132-238)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	66.667	99.051	0.66
uvrA	Streptococcus pneumoniae TIGR4	66.667	99.051	0.66
uvrA	Streptococcus pneumoniae D39	66.667	99.051	0.66