Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   KU528_RS01395 Genome accession   NZ_CP077865
Coordinates   279846..280553 (+) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain 370     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 274846..285553
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU528_RS01340 (KU528_01330) - 275600..275863 (-) 264 WP_001205732.1 hypothetical protein -
  KU528_RS01345 (KU528_01335) - 275872..276132 (-) 261 WP_000291489.1 DUF1108 family protein -
  KU528_RS01350 (KU528_01340) - 276225..276386 (-) 162 WP_000066020.1 DUF1270 domain-containing protein -
  KU528_RS01355 (KU528_01345) - 276383..276703 (-) 321 WP_001120197.1 DUF771 domain-containing protein -
  KU528_RS01360 (KU528_01350) - 276762..277394 (+) 633 WP_000275058.1 hypothetical protein -
  KU528_RS01365 (KU528_01355) - 277409..277549 (-) 141 WP_000939496.1 hypothetical protein -
  KU528_RS01370 (KU528_01360) - 277580..277774 (-) 195 WP_000388066.1 hypothetical protein -
  KU528_RS01375 (KU528_01365) - 277791..278543 (-) 753 WP_225805747.1 phage antirepressor KilAC domain-containing protein -
  KU528_RS01380 (KU528_01370) - 278600..279139 (+) 540 WP_000351243.1 hypothetical protein -
  KU528_RS01385 (KU528_01375) - 279163..279423 (-) 261 WP_000435341.1 transcriptional regulator -
  KU528_RS01390 (KU528_01380) - 279436..279675 (-) 240 WP_000548578.1 helix-turn-helix transcriptional regulator -
  KU528_RS01395 (KU528_01385) irvR 279846..280553 (+) 708 WP_000094093.1 helix-turn-helix domain-containing protein Regulator
  KU528_RS01400 (KU528_01390) - 280565..280720 (+) 156 WP_001049399.1 hypothetical protein -
  KU528_RS01405 (KU528_01395) - 280707..280892 (+) 186 WP_001089804.1 hypothetical protein -
  KU528_RS01410 (KU528_01400) - 281092..281208 (+) 117 Protein_281 hypothetical protein -
  KU528_RS01415 (KU528_01405) istB 281268..282029 (-) 762 WP_001066124.1 IS21-like element helper ATPase IstB -
  KU528_RS01420 (KU528_01410) istA 282022..283314 (-) 1293 WP_000777467.1 IS21 family transposase -
  KU528_RS01425 - 283395..283466 (+) 72 Protein_284 hypothetical protein -
  KU528_RS01430 (KU528_01415) - 283606..284145 (+) 540 WP_000391618.1 type II toxin-antitoxin system PemK/MazF family toxin -
  KU528_RS01435 (KU528_01420) - 284318..285355 (+) 1038 WP_000857198.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=509029 KU528_RS01395 WP_000094093.1 279846..280553(+) (irvR) [Staphylococcus aureus strain 370]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=509029 KU528_RS01395 WP_000094093.1 279846..280553(+) (irvR) [Staphylococcus aureus strain 370]
ATGAGTTCATTTTCTTCGAATTTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTTAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTATCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374