Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   KU510_RS12190 Genome accession   NZ_CP077861
Coordinates   2473636..2475417 (+) Length   593 a.a.
NCBI ID   WP_000390527.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 372     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2468636..2480417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU510_RS12170 (KU510_12125) polX 2468755..2470467 (+) 1713 WP_000161946.1 DNA polymerase/3'-5' exonuclease PolX -
  KU510_RS12175 (KU510_12130) mutS/mutS2 2470477..2472825 (+) 2349 WP_001249291.1 endonuclease MutS2 Machinery gene
  KU510_RS12180 (KU510_12135) trxA 2472998..2473312 (+) 315 WP_001018928.1 thioredoxin -
  KU510_RS12185 (KU510_12140) - 2473375..2473470 (-) 96 WP_031844936.1 hypothetical protein -
  KU510_RS12190 (KU510_12145) uvrC 2473636..2475417 (+) 1782 WP_000390527.1 excinuclease ABC subunit UvrC Machinery gene
  KU510_RS12195 (KU510_12150) - 2475741..2476355 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  KU510_RS12200 (KU510_12155) sdhA 2476407..2478173 (+) 1767 WP_000818283.1 succinate dehydrogenase flavoprotein subunit -
  KU510_RS12205 (KU510_12160) sdhB 2478173..2478988 (+) 816 WP_000139712.1 succinate dehydrogenase iron-sulfur subunit -
  KU510_RS12210 (KU510_12165) racE 2479229..2480029 (+) 801 WP_001039658.1 glutamate racemase -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68629.32 Da        Isoelectric Point: 9.7476

>NTDB_id=508909 KU510_RS12190 WP_000390527.1 2473636..2475417(+) (uvrC) [Staphylococcus aureus strain 372]
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLL
ELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKI
MSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMI
QSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSA
MVTFVDGKPDKKNYRKYKIKTVIGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVA
GLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGSKRKTLLLRSF
GSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=508909 KU510_RS12190 WP_000390527.1 2473636..2475417(+) (uvrC) [Staphylococcus aureus strain 372]
TTGGAAGACTATAAGCAACGAATTAAAAATAAATTAAATGTCGTACCTATGGAACCAGGCTGCTATTTAATGAAAGATCG
TAATGATCAAGTGATATATGTTGGCAAAGCTAAAAAGCTAAGAAATCGATTGCGATCATATTTTACGGGCGCTCATGATG
CTAAAACAACGAGACTGGTTGGTGAAATACGTCGCTTTGAGTTTATTGTCACGTCTAGTGAAACAGAGTCACTTTTACTT
GAATTGAATCTGATTAAACAATATCAACCTAGATACAACATTTTATTAAAAGATGATAAAAGTTATCCATTTATTAAAAT
TACGAAGGAAAAATATCCTAGACTACTAGTGACGAGAACTGTAAAACAAGGTACTGGCAAATATTTCGGACCGTATCCGA
ATGCATATTCTGCTCAAGAAACTAAAAAATTATTAGACAGAATATATCCATATCGCAAATGTGATAAGATGCCAGATAAA
TTATGTCTTTATTACCATATTGGACAATGTTTAGGACCATGTGTATATGACGTTGATTTGAGTAAATACGCACAAATGAC
GAAGGAAATTACTGATTTTCTGAATGGGGAAGACAAAACAATTTTAAAAAGTTTAGAAGAGCGAATGTTAACTGCAAGTG
AATCACTTGATTTTGAACGAGCTAAAGAATATAGAGATTTAATTCAACATATTCAAAATCTAACTAACAAACAAAAAATT
ATGTCATCAGATAAAACGATTCGTGATGTCTTTGGTTATAGTGTTGATAAAGGATGGATGTGTATCCAAGTTTTCTTTAT
ACGACAAGGTAATATGATAAAGCGAGATACAACGATGATTCCATTACAGCAAACAGAAGAAGAAGAATTTTATACATTTA
TTGGACAATTTTATAGCTTAAACCAACATATTTTACCTAAGGAAGTTCATGTACCACGTAATTTGGATAAAGAAATGATT
CAATCTGTTGTGGACACTAAAATCGTTCAACCCGCGCGAGGTCCCAAAAAAGATATGGTTGACCTAGCTGCACATAACGC
TAAAGTATCCTTAAATAATAAATTTGAATTAATATCACGTGATGAGTCCAGAACAATTAAAGCTATTGAAGAACTTGGAA
CACAAATGGGAATTCAAACACCAATTAGAATTGAAGCATTCGATAATTCTAATATTCAAGGTGTGGATCCAGTGTCAGCA
ATGGTTACATTTGTCGACGGTAAACCAGACAAGAAAAATTATAGAAAGTATAAAATCAAAACGGTTATAGGTCCAGATGA
TTACAAATCAATGAGAGAAGTAGTAAGACGACGATATTCTCGCGTTTTAAACGAAGGATTACCATTACCTGATTTAATAA
TAGTAGATGGTGGTAAAGGACATATGAACGGGGTTATTGATGTGCTACAAAACGAATTAGGTCTTGATATCCCTGTTGCA
GGTTTGCAAAAAAATGATAAACACCAAACATCTGAATTATTATATGGCGCTAGTGCAGAAATTGTACCACTGAAGAAAAA
TAGCCAAGCATTTTATTTGTTGCACCGTATCCAAGATGAGGTTCACAGATTCGCAATCACCTTTCATAGACAAACACGTC
AAAAGACCGGCTTGAAATCAATACTTGATGATATAGATGGTATCGGTAGCAAACGTAAAACATTATTATTGCGTTCATTC
GGTTCAATCAAGAAAATGAAGGAAGCTACACTTGAAGATTTTAAAAATATAGGTATTCCTGAAAACGTTGCAAAGAACCT
ACATGAACAATTGCATAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(200-233)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-526)

GIY-YIG catalytic domain (GIY-YIG)

(19-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae R6

57.436

98.651

0.567
  uvrC Streptococcus pneumoniae D39

57.436

98.651

0.567