Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I5046_RS09790 Genome accession   NZ_CP065355
Coordinates   2005135..2005851 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain JW31330_O1_dhc     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2000135..2010851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5046_RS09760 (I5046_09760) - 2000368..2000994 (+) 627 WP_000522389.1 nitroreductase family protein -
  I5046_RS09765 (I5046_09765) - 2001356..2002141 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  I5046_RS09770 (I5046_09770) hld 2002723..2002803 (-) 81 WP_000046022.1 delta-hemolysin -
  I5046_RS09775 (I5046_09775) - 2003094..2003657 (+) 564 WP_001105698.1 accessory gene regulator AgrB -
  I5046_RS09780 (I5046_09780) agrD 2003660..2003803 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  I5046_RS09785 (I5046_09785) agrC 2003833..2005116 (+) 1284 WP_000447894.1 quorum-sensing sensor histidine kinase AgrC -
  I5046_RS09790 (I5046_09790) agrA 2005135..2005851 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  I5046_RS09795 (I5046_09795) - 2005923..2006030 (+) 108 WP_031927342.1 hypothetical protein -
  I5046_RS09800 (I5046_09800) - 2006218..2007177 (-) 960 WP_001253297.1 carbohydrate kinase family protein -
  I5046_RS09805 (I5046_09805) - 2007174..2008658 (-) 1485 WP_000141418.1 sucrose-6-phosphate hydrolase -
  I5046_RS09810 (I5046_09810) - 2008807..2009757 (-) 951 WP_000790320.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=508804 I5046_RS09790 WP_000688492.1 2005135..2005851(+) (agrA) [Staphylococcus aureus strain JW31330_O1_dhc]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=508804 I5046_RS09790 WP_000688492.1 2005135..2005851(+) (agrA) [Staphylococcus aureus strain JW31330_O1_dhc]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1