Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   I5046_RS07170 Genome accession   NZ_CP065355
Coordinates   1530212..1531186 (-) Length   324 a.a.
NCBI ID   WP_000697220.1    Uniprot ID   W8U5L8
Organism   Staphylococcus aureus strain JW31330_O1_dhc     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1525212..1536186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5046_RS07130 (I5046_07130) gcvT 1525713..1526804 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  I5046_RS07135 (I5046_07135) - 1526963..1527487 (-) 525 WP_001015120.1 shikimate kinase -
  I5046_RS07140 (I5046_07140) - 1527477..1527623 (-) 147 WP_001789879.1 hypothetical protein -
  I5046_RS07145 (I5046_07145) comGF 1527720..1528217 (-) 498 WP_029693246.1 competence type IV pilus minor pilin ComGF Machinery gene
  I5046_RS07150 (I5046_07150) comGE 1528135..1528434 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  I5046_RS07155 (I5046_07155) comGD 1528421..1528867 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  I5046_RS07160 (I5046_07160) comGC 1528845..1529156 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  I5046_RS07165 (I5046_07165) comGB 1529170..1530240 (-) 1071 WP_000776407.1 competence type IV pilus assembly protein ComGB Machinery gene
  I5046_RS07170 (I5046_07170) comGA 1530212..1531186 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  I5046_RS07175 (I5046_07175) - 1531238..1531861 (-) 624 WP_123138722.1 MBL fold metallo-hydrolase -
  I5046_RS07180 (I5046_07180) - 1531858..1532187 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  I5046_RS07185 (I5046_07185) - 1532187..1533173 (-) 987 WP_000161315.1 ROK family glucokinase -
  I5046_RS07190 (I5046_07190) - 1533170..1533373 (-) 204 WP_000087561.1 YqgQ family protein -
  I5046_RS07195 (I5046_07195) - 1533354..1534817 (-) 1464 WP_001017869.1 rhomboid family protein -
  I5046_RS07200 (I5046_07200) - 1534829..1535368 (-) 540 WP_000164548.1 5-formyltetrahydrofolate cyclo-ligase -
  I5046_RS07205 (I5046_07205) rpmG 1535577..1535726 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36897.96 Da        Isoelectric Point: 8.8516

>NTDB_id=508790 I5046_RS07170 WP_000697220.1 1530212..1531186(-) (comGA) [Staphylococcus aureus strain JW31330_O1_dhc]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=508790 I5046_RS07170 WP_000697220.1 1530212..1531186(-) (comGA) [Staphylococcus aureus strain JW31330_O1_dhc]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCCTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTAATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAGGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8U5L8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

100

100

1
  comGA Staphylococcus aureus N315

100

100

1