Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I5044_RS09810 Genome accession   NZ_CP065354
Coordinates   2014398..2015114 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain JW_comp_novo     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2009398..2020114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5044_RS09780 (I5044_09780) - 2009631..2010257 (+) 627 WP_000522389.1 nitroreductase family protein -
  I5044_RS09785 (I5044_09785) - 2010619..2011404 (+) 786 WP_000867953.1 carbon-nitrogen family hydrolase -
  I5044_RS09790 (I5044_09790) hld 2011986..2012066 (-) 81 WP_000046022.1 delta-hemolysin -
  I5044_RS09795 (I5044_09795) - 2012357..2012920 (+) 564 WP_001105698.1 accessory gene regulator AgrB -
  I5044_RS09800 (I5044_09800) agrD 2012923..2013066 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  I5044_RS09805 (I5044_09805) agrC 2013096..2014379 (+) 1284 WP_000447894.1 quorum-sensing sensor histidine kinase AgrC -
  I5044_RS09810 (I5044_09810) agrA 2014398..2015114 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  I5044_RS09815 (I5044_09815) - 2015186..2015293 (+) 108 WP_031927342.1 hypothetical protein -
  I5044_RS09820 (I5044_09820) - 2015481..2016440 (-) 960 WP_001253297.1 carbohydrate kinase family protein -
  I5044_RS09825 (I5044_09825) - 2016437..2017921 (-) 1485 WP_000141418.1 sucrose-6-phosphate hydrolase -
  I5044_RS09830 (I5044_09830) - 2018070..2019020 (-) 951 WP_000790320.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=508762 I5044_RS09810 WP_000688492.1 2014398..2015114(+) (agrA) [Staphylococcus aureus strain JW_comp_novo]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=508762 I5044_RS09810 WP_000688492.1 2014398..2015114(+) (agrA) [Staphylococcus aureus strain JW_comp_novo]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1