Detailed information NTG0050815

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: MYY_RS06285
• Genome accession: NC_017769
• Coordinates: 1207399..1208352 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae ST556
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1202399..1213352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MYY_RS12710	-	1202889..1202984 (-)	96	Protein_1215	IS630 family transposase	-
MYY_RS06265 (MYY_02925)	-	1203397..1203738 (+)	342	Protein_1216	transposase	-
MYY_RS06270 (MYY_1224)	prsA	1203855..1204796 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
MYY_RS06275 (MYY_1225)	-	1204863..1205576 (-)	714	WP_000230400.1	O-methyltransferase	-
MYY_RS06280 (MYY_1226)	pepF	1205578..1207380 (-)	1803	WP_000244159.1	oligoendopeptidase F	Regulator
MYY_RS06285 (MYY_1227)	coiA	1207399..1208352 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
MYY_RS06290 (MYY_1228)	tehB	1208425..1209285 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
MYY_RS06295 (MYY_1229)	smpB	1209301..1209768 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
MYY_RS06300 (MYY_1230)	rnr	1209731..1212085 (-)	2355	WP_000654886.1	ribonuclease R	-
MYY_RS06305 (MYY_1231)	secG	1212187..1212420 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
MYY_RS06310 (MYY_02930)	rpmG	1212460..1212609 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=50815 MYY_RS06285 WP_000495909.1 1207399..1208352(-) (coiA) [Streptococcus pneumoniae ST556]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=50815 MYY_RS06285 WP_000495909.1 1207399..1208352(-) (coiA) [Streptococcus pneumoniae ST556]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435